Faculty of Dentistry, SEGi University, Petaling Jaya, Selangor, Malaysia, e-mail:
Department of Prosthodontics and Restorative Dentistry, School of Dentistry, College of Medicine and Health Sciences, University of Rwanda, Remera Campus, Kigali, Rwanda.
J Contemp Dent Pract. 2021 Oct 1;22(10):1079-1081.
Autophagy, first described by the Belgian biochemist Christian De Duve in 1963, is derived from the Greek word "autóphagos," which means "self-devouring." It is a cellular homeostatic process in which the body rids itself of flawed or damaged cells and other defective cellular organelles. The implication of defective autophagy in various human diseases has been well documented. The vital importance of autophagy is underscored by the fact that robust cellular health and function are intricately linked with it.
自噬，由比利时生物化学家 Christian De Duve 在 1963 年首次描述，源自希腊语"autóphagos"，意为"自我吞噬"。它是一种细胞内稳态过程，身体通过该过程清除有缺陷或受损的细胞和其他有缺陷的细胞器。自噬缺陷与各种人类疾病的关联已得到充分证实。自噬的重要性不言而喻，因为它与细胞的健康和功能密切相关。
