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《东日本大地震后的家庭健康:东北医疗 Mega 银行项目出生及三代队列研究的结果》。

Families' Health after the Great East Japan Earthquake: Findings from the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study.

机构信息

Department of Preventive Medicine and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University.

Division of Molecular Epidemiology, Tohoku University Graduate School of Medicine.

出版信息

Tohoku J Exp Med. 2022 Feb;256(2):93-101. doi: 10.1620/tjem.256.93.

DOI:10.1620/tjem.256.93
PMID:35197407
Abstract

Infectious diseases, chronic diseases, and mental disorders in both adults and children are reported after disasters occur. The correlation between chronic diseases and mental disorders has also been reported. Moreover, disasters may affect perinatal outcomes. Thus, both adult and child health should be carefully monitored in disaster aftermath. A prospective cohort study of pregnant women and their families, the Tohoku Medical Megabank Project (TMM) Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study), has been conducted since 2013. A total of 73,529 family members participated in the TMM BirThree Cohort Study. Among siblings, the proportion of "small for gestational age" was the same in the pre- and post-disaster periods. Among parents and grandparents who answered the baseline questionnaire, 5.6% in the inland area and 19.8% in the coastal area had their houses totally/mostly destroyed by the Great East Japan Earthquake. Although a depression trend due to house damage was not observed in mothers, the proportion of psychological distress was high according to house damage (P for trend = 0.04). Among parents, there was an increase in overweight persons (P for trend = 0.004 in mothers and < 0.0001 in fathers) and in the number of smokers based on the severity of house damage (P for trend = 0.002 in mothers and < 0.0001 in fathers), whereas no such trend was observed in grandparents. Continuous monitoring and support for those who need are essential. Moreover, utilizing existing cohort studies to investigate health status when we face a new disaster is desirable.

摘要

灾难发生后,报告称成年人和儿童都患有传染病、慢性病和精神障碍。也有报告称慢性病与精神障碍之间存在关联。此外,灾害可能会影响围产期结局。因此,灾难后应仔细监测成人和儿童的健康状况。自 2013 年以来,一项针对孕妇及其家庭的前瞻性队列研究——东北医疗中心巨型生物银行项目(Tohoku Medical Megabank Project,TMM)母婴三代队列研究(TMM BirThree Cohort Study)一直在进行。共有 73529 名家庭成员参加了 TMM BirThree 队列研究。在兄弟姐妹中,“小于胎龄儿”的比例在灾前和灾后时期相同。在回答基线问卷的父母和祖父母中,内陆地区有 5.6%、沿海地区有 19.8%的房屋全部/大部分被东日本大地震摧毁。尽管母亲中没有观察到因房屋受损而导致的抑郁趋势,但根据房屋受损情况,心理困扰的比例较高(趋势 P = 0.04)。在父母中,超重者人数有所增加(母亲中呈上升趋势,P = 0.004;父亲中呈显著上升趋势,P < 0.0001),且根据房屋受损程度,吸烟者人数也有所增加(母亲中呈上升趋势,P = 0.002;父亲中呈显著上升趋势,P < 0.0001),但在祖父母中没有这种趋势。需要对那些需要的人进行持续监测和支持。此外,在面对新的灾难时,利用现有的队列研究来调查健康状况是可取的。

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