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皮下注射地塞米松对减少隆鼻患者水肿和瘀斑的作用。

The Effect of Subcutaneous Dexamethasone to Reduce Edema and Ecchymosis in Rhinoplasty Patients.

作者信息

Jafari Mahboubeh, Maleki Delarestaghi Mojtaba, Jahandideh Hesam, Rajaeih Shahin, Ghashghaei Sara, Wood David A

机构信息

ENT and Head & Neck Research Center, The Five Senses Institute, Iran University of Medical Science, Tehran, Iran.

Department of Otolaryngology Head and Neck Surgery, Firoozgar Hospital, Iran University of Medical Science, Tehran, Iran.

出版信息

Int J Otolaryngol. 2022 Feb 14;2022:3054767. doi: 10.1155/2022/3054767. eCollection 2022.

DOI:10.1155/2022/3054767
PMID:35198028
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8860562/
Abstract

BACKGROUND

Rhinoplasty is one of the most common types of cosmetic surgery undertaken. In most rhinoplasty patients, an osteotomy is used to reshape the nasal pyramid. The most common complications following osteotomy are edema and ecchymosis. Edema and ecchymosis have a significant effect on a patients' satisfaction with surgery and their return to social activities. For this purpose, various methods have been used to reduce edema and ecchymosis, including intravenous injection of corticosteroids, cold compresses, and tranexamic acid.

OBJECTIVE

To reduce edema and ecchymosis in rhinoplasty patients by administering a subcutaneous injection of dexamethasone and thereby prevent unwanted systemic side effects of corticosteroid treatments.

METHOD

We conduct a hospital-based nonrandomised study of rhinoplasty patients, with their informed consent treated over the course of one year. Dexamethasone was injected on one side of consenting patient's face immediately before surgery and the results were compared with the opposite side that was not injected. The face images of patients were taken on the front view on the first, third, seventh, and fourteenth days following the treatment. The grade of edema and ecchymosis encountered in each patient was determined by three ENT specialists. The degree of edema and ecchymosis was compared on the injected and noninjected sides and the findings were statistically analysed. The nonrandomised study considered 42 rhinoplasty patients. The mean age of patients was 27.9 years and their age ranged between 17 and 52 years. For 20 patients (47.6%), injection was performed on the right side, and for 22 patients (52.3%), injection was performed on the left side. . The statistical analysis of patient outcomes reveals that a supraperiosteal injection of dexamethasone was not effective in reducing edema and ecchymosis after rhinoplasty.

摘要

背景

隆鼻术是最常见的整形手术类型之一。在大多数隆鼻患者中,会采用截骨术来重塑鼻锥体。截骨术后最常见的并发症是水肿和瘀斑。水肿和瘀斑对患者对手术的满意度以及他们恢复社交活动有显著影响。为此,人们采用了各种方法来减轻水肿和瘀斑,包括静脉注射皮质类固醇、冷敷和氨甲环酸。

目的

通过皮下注射地塞米松减轻隆鼻患者的水肿和瘀斑,从而预防皮质类固醇治疗产生的不良全身副作用。

方法

我们对隆鼻患者进行了一项基于医院的非随机研究,在一年的时间里,在患者知情同意的情况下进行治疗。在同意治疗的患者面部一侧,于手术前立即注射地塞米松,并将结果与未注射的对侧进行比较。在治疗后的第一天、第三天、第七天和第十四天,从正面拍摄患者的面部图像。由三位耳鼻喉科专家确定每位患者出现的水肿和瘀斑等级。比较注射侧和未注射侧的水肿和瘀斑程度,并对结果进行统计分析。该非随机研究纳入了42例隆鼻患者。患者的平均年龄为27.9岁,年龄范围在17至52岁之间。20例患者(47.6%)在右侧进行注射,22例患者(52.3%)在左侧进行注射。对患者结果的统计分析表明,骨膜上注射地塞米松对减轻隆鼻术后的水肿和瘀斑无效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf69/8860562/1965fa1da0ad/ijoto2022-3054767.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf69/8860562/94117ef9fd6b/ijoto2022-3054767.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf69/8860562/57954fd5a89c/ijoto2022-3054767.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf69/8860562/1965fa1da0ad/ijoto2022-3054767.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf69/8860562/94117ef9fd6b/ijoto2022-3054767.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf69/8860562/57954fd5a89c/ijoto2022-3054767.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bf69/8860562/1965fa1da0ad/ijoto2022-3054767.003.jpg

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Efficacy of Dexamethasone for Reducing Edema and Ecchymosis After Rhinoplasty: A Systematic Review and Meta-analysis.地塞米松减少鼻整形术后水肿和瘀斑的疗效:系统评价和荟萃分析。
Aesthetic Plast Surg. 2020 Oct;44(5):1672-1684. doi: 10.1007/s00266-020-01743-w. Epub 2020 May 7.
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