Demir Ömer Faruk, Onal Omer
Department of Thoracic Surgery, Faculty of Medicine, University of Erciyes, Kayseri, Turkey.
Ann Thorac Med. 2022 Jan-Mar;17(1):44-50. doi: 10.4103/atm.atm_119_21. Epub 2022 Jan 14.
Pulmonary inflammatory myofibroblastic tumor (PIMT) is an extremely rare disease. The aim of this study was to share the surgical outcomes of these tumors.
Patients who were operated for pulmonary myofibroblastic tumors between January 2005 and January 2021 were determined by retrospectively scanning patient files. Patients' demographic characteristics, tumor location, surgical techniques, and other parameters were obtained from the patient files. The KaplanMeier method was used for survival calculations, whereas the log-rank test was used for comparison of survival calculations.
PIMTs were noted in 14 patients (0.12%) in a total of 11,108 thoracic procedures performed in our institution between January 2005 and January 2021. The mean age of the patients was 28.2 (range: 2-67) years. Of the patients, six were male and eight were female, with 50% ( = 7) aged under 18 years. A total of 17 surgical procedures were performed on 14 patients. One patient underwent pneumonectomy, two patients lobectomy, ten0 patients wedge resection, and one patient underwent debulking surgery. A total of 11 patients had complete surgery, whereas three patients had incomplete surgery. The 10-year overall survival was 84.6% and the 10-year disease-free survival (DFS) was 75.0%. Complete resection was found to be the only and significant factor that had an effect on survival ( = 0.004) and DFS ( = 0.012).
PIMTs are extremely rare. Complete surgery should be considered an effective factor in survival and DFS.
肺炎性肌纤维母细胞瘤（PIMT）是一种极其罕见的疾病。本研究的目的是分享这些肿瘤的手术结果。
通过回顾性查阅患者病历，确定2005年1月至2021年1月间接受肺肌纤维母细胞瘤手术的患者。从患者病历中获取患者的人口统计学特征、肿瘤位置、手术技术和其他参数。采用Kaplan-Meier方法进行生存计算，而对数秩检验用于比较生存计算结果。
在2005年1月至2021年1月期间，我们机构共进行了11108例胸科手术，其中14例患者（0.12%）被诊断为PIMT。患者的平均年龄为28.2岁（范围：2 - 67岁）。患者中，6例为男性，8例为女性，50%（n = 7）年龄在18岁以下。14例患者共进行了17次手术。1例患者接受了全肺切除术，2例患者接受了肺叶切除术，10例患者接受了楔形切除术，1例患者接受了减瘤手术。共有11例患者接受了完整手术，而3例患者接受了不完整手术。10年总生存率为84.6%，10年无病生存率（DFS）为75.0%。发现完整切除是影响生存（P = 0.004）和DFS（P = 0.012）的唯一且显著的因素。
PIMT极其罕见。完整手术应被视为影响生存和DFS的有效因素。
