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左回旋支完全闭塞的非ST段抬高型心肌梗死:N波可能如何发挥作用(病例报告)

NSTEMI with total left circumflex occlusion: how the N-wave might help (case report).

作者信息

Alsagaff Mochamad Yusuf, Wardhani Louisa Fadjri Kusuma, Pratanu Iswanto, Kartikasari Dian Paramita, Doevendans Pieter A

机构信息

Department of Cardiology and Vascular Medicine, Faculty of Medicine, Airlangga University-Dr Soetomo General Hospital Surabaya, Surabaya, Indonesia.

Department of Cardiology, University Medical Center Utrecht, Utrecht, Netherland.

出版信息

Oxf Med Case Reports. 2022 Feb 19;2022(2):omac010. doi: 10.1093/omcr/omac010. eCollection 2022 Feb.

DOI:10.1093/omcr/omac010
PMID:35198230
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8858395/
Abstract

A rise and/or fall in troponin level is an indication of type 1 or 2 myocardial infarct. A 62-year-old male physician presented to emergency room with chest discomfort followed by thought to be normal electrocardiogram (ECG) and normal echocardiography results. His serial hs-troponin test showed remarkable escalation three hours from the initial (107 ng/l into 4.978 ng/l), suggesting a high-risk non-ST-segment myocardial infarction (NSTEMI). An early invasive procedure was performed, showing acute total occlusion (TO) in the obtuse marginal 1 branch. We retrospectively reviewed our examination to diagnose better the presence of TO in NSTEMI patients presented with non-diagnostic examination. Our evaluation showed a minor change in the form of an 'N-wave' pattern on the ECG, which was not yet an established guideline criterion for prompt angiography. Although ECG pattern is often normal in LCx occlusion, recent study shows the presence of 'N-wave' ECG pattern in 10% of NSTEMI cases following TO at LCx.

摘要

肌钙蛋白水平的升高和/或降低表明1型或2型心肌梗死。一名62岁的男性医生因胸部不适前往急诊室,随后心电图(ECG)和超声心动图结果被认为正常。他的系列高敏肌钙蛋白检测显示,从最初的检测结果(107纳克/升升至4978纳克/升)开始,三小时内显著升高,提示高危非ST段心肌梗死(NSTEMI)。进行了早期侵入性检查,显示钝缘支1急性完全闭塞(TO)。我们回顾性地检查了我们的检查情况,以便更好地诊断在检查未明确诊断的NSTEMI患者中TO的存在情况。我们的评估显示,心电图上出现了一种轻微变化,表现为“N波”模式,但这尚未成为提示进行血管造影的既定指南标准。尽管在左回旋支闭塞时心电图模式通常正常,但最近的研究表明,在左回旋支发生TO后的NSTEMI病例中,有10%出现“N波”心电图模式。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f741/8858395/a0aca7774822/omac010f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f741/8858395/8ff3179dfbf6/omac010f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f741/8858395/6243b293b6bf/omac010f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f741/8858395/80510d94b569/omac010f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f741/8858395/a0aca7774822/omac010f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f741/8858395/8ff3179dfbf6/omac010f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f741/8858395/6243b293b6bf/omac010f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f741/8858395/80510d94b569/omac010f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f741/8858395/a0aca7774822/omac010f4.jpg

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本文引用的文献

1
Accuracy of OMI ECG findings versus STEMI criteria for diagnosis of acute coronary occlusion myocardial infarction.与ST段抬高型心肌梗死(STEMI)诊断标准相比,OMI心电图表现对急性冠状动脉闭塞性心肌梗死的诊断准确性。
Int J Cardiol Heart Vasc. 2021 Apr 12;33:100767. doi: 10.1016/j.ijcha.2021.100767. eCollection 2021 Apr.
2
Non-ST-elevated myocardial infarction with "N" wave on electrocardiogram and culprit vessel in left circumflex has a risk equivalent to ST-elevated myocardial infarction.心电图有“N”波的非 ST 段抬高型心肌梗死伴左回旋支罪犯血管与 ST 段抬高型心肌梗死具有同等风险。
Clin Cardiol. 2020 May;43(5):491-499. doi: 10.1002/clc.23334. Epub 2020 Feb 7.
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Impact of total occlusion of culprit artery in acute non-ST elevation myocardial infarction: a systematic review and meta-analysis.
罪犯动脉完全闭塞对急性非 ST 段抬高型心肌梗死的影响:系统评价和荟萃分析。
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Anatomic distribution of culprit lesions in patients with non-ST-segment elevation myocardial infarction and normal ECG.非ST段抬高型心肌梗死且心电图正常患者罪犯病变的解剖分布
Cardiovasc Diagn Ther. 2016 Feb;6(1):25-33. doi: 10.3978/j.issn.2223-3652.2015.10.05.
6
ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: The Task Force for the management of acute coronary syndromes (ACS) in patients presenting without persistent ST-segment elevation of the European Society of Cardiology (ESC).欧洲心脏病学会(ESC)非持续性ST段抬高型急性冠状动脉综合征患者管理指南:欧洲心脏病学会(ESC)非持续性ST段抬高型急性冠状动脉综合征(ACS)管理工作组。
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