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妊娠肝内胆汁淤积症：一份病例报告自述

Intrahepatic Cholestasis of Pregnancy: An Autobiographical Case Report.

作者信息

Bartolone Samantha, Alexis Renee

机构信息

Osteopathic Medicine, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Davie, USA.

Obstetrics and Gynecology, Nova Southeastern University Dr. Kiran C. Patel College of Osteopathic Medicine, Davie, USA.

出版信息

Cureus. 2022 Jan 18;14(1):e21366. doi: 10.7759/cureus.21366. eCollection 2022 Jan.

DOI:10.7759/cureus.21366
PMID:35198280
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8854202/
Abstract

Intrahepatic cholestasis of pregnancy (ICP) is the most common liver disorder of pregnancy. This case report describes the author's experience of being diagnosed with the condition, the course of treatment and outcome for her baby, and the emotional aspects of the disease.

摘要

妊娠期肝内胆汁淤积症（ICP）是妊娠期最常见的肝脏疾病。本病例报告描述了作者被诊断出患有该病的经历、治疗过程及对其宝宝的结局，以及该疾病的情感方面。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96a2/8854202/c6322080d160/cureus-0014-00000021366-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96a2/8854202/c6322080d160/cureus-0014-00000021366-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/96a2/8854202/c6322080d160/cureus-0014-00000021366-i01.jpg

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本文引用的文献

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Prevalence and risk factors of intrahepatic cholestasis of pregnancy in a Chinese population.中国人群妊娠肝内胆汁淤积症的流行状况及危险因素。
Sci Rep. 2020 Oct 1;10(1):16307. doi: 10.1038/s41598-020-73378-5.
2
Perinatal outcomes of intrahepatic cholestasis during pregnancy: An 8-year case-control study.妊娠期肝内胆汁淤积症的围产儿结局：一项 8 年的病例对照研究。
PLoS One. 2020 Feb 19;15(2):e0228213. doi: 10.1371/journal.pone.0228213. eCollection 2020.
3
Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data meta-analyses.
妊娠肝内胆汁淤积症不良围产结局与生化标志物的关联：汇总和个体患者数据荟萃分析结果。
Lancet. 2019 Mar 2;393(10174):899-909. doi: 10.1016/S0140-6736(18)31877-4. Epub 2019 Feb 14.
4
Intrahepatic cholestasis of pregnancy: Review of six national and regional guidelines.妊娠期肝内胆汁淤积症：六项国家和地区指南综述
Eur J Obstet Gynecol Reprod Biol. 2018 Dec;231:180-187. doi: 10.1016/j.ejogrb.2018.10.041. Epub 2018 Oct 26.
5
Intrahepatic Cholestasis of Pregnancy: A Review of Diagnosis and Management.妊娠肝内胆汁淤积症：诊断与管理的综述。
Obstet Gynecol Surv. 2018 Feb;73(2):103-109. doi: 10.1097/OGX.0000000000000524.
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An expanded role for heterozygous mutations of ABCB4, ABCB11, ATP8B1, ABCC2 and TJP2 in intrahepatic cholestasis of pregnancy.ABCB4、ABCB11、ATP8B1、ABCC2 和 TJP2 的杂合突变在妊娠肝内胆汁淤积症中的作用扩大。
Sci Rep. 2017 Sep 18;7(1):11823. doi: 10.1038/s41598-017-11626-x.
7
The risk of infant and fetal death by each additional week of expectant management in intrahepatic cholestasis of pregnancy by gestational age.妊娠肝内胆汁淤积症中，按孕周计算，期待治疗每增加一周，胎儿及婴儿死亡的风险。
Am J Obstet Gynecol. 2015 Oct;213(4):593. doi: 10.1016/j.ajog.2015.06.003. Epub 2015 Jun 9.
8
Neonatal outcomes and delivery of care for infants born late preterm or moderately preterm: a prospective population-based study.新生儿结局和晚期早产儿或中度早产儿的护理提供：一项前瞻性基于人群的研究。
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Maternal cholestasis during pregnancy programs metabolic disease in offspring.孕妇在怀孕期间发生的胆汁淤积会导致后代发生代谢疾病。
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