Al Saad Ali J, Buhalim Rayan A, Al Jabr Faisal A, Al Dehailan Abdulaziz M, Albahrani Abdulaziz A
Clinical Neuroscience, King Faisal University, Al-Ahsa, SAU.
College of Medicine, King Faisal University, Al-Ahsa, SAU.
Cureus. 2022 Jan 18;14(1):e21367. doi: 10.7759/cureus.21367. eCollection 2022 Jan.
Sickle cell disease (SCD) is among the common prevalent diseases in Saudi Arabia. It is associated with several complications that sometimes necessitate surgical procedures. Those patients can also have a lower quality of life (QoL) due to several reasons. Our aim in this study is to highlight the association between sociodemographic data, clinical data, and SCD-related surgeries in patients with their QoL.
A cross-sectional study was performed using a validated Arabic version of the World Health Organization QoL-BREF (WHOQOL-BREF) questionnaire distributed in electronic form. Male and female Arabic speakers (18+ years old) of Saudi origin were included in this study; those who did not meet these criteria were excluded.
We distributed 309 questionnaires to the targeted subjects; however, only 204 met our inclusion criteria. Our findings revealed 135 female respondents and 69 male respondents. Interestingly, splenectomy was not significantly associated with a difference in all aspects of QoL in SCD patients. However, the data showed significantly lower respective mean scores for physical health (p=0.002 & p=0.022) and overall QoL (p=0.024 & p=0.042) for those who underwent cholecystectomy and hip arthroplasty. In contrast, shoulder arthroplasty appeared to be associated with significantly lower mean scores for physical health (T=-2.597; p=0.010) and the environmental aspect of QoL (T=-2.016; p=0.045).
Cholecystectomy, hip arthroplasty, and shoulder arthroplasty were significantly associated with lower QoL in SCD patients.
镰状细胞病（SCD）是沙特阿拉伯常见的流行疾病之一。它与多种并发症相关，有时需要进行外科手术。由于多种原因，这些患者的生活质量（QoL）也可能较低。本研究的目的是强调社会人口统计学数据、临床数据以及SCD相关手术与患者生活质量之间的关联。
采用经验证的阿拉伯语版世界卫生组织生活质量简表（WHOQOL-BREF）问卷以电子形式进行横断面研究。纳入沙特籍讲阿拉伯语的18岁及以上男性和女性；不符合这些标准的被排除。
我们向目标受试者发放了309份问卷；然而，只有204份符合我们的纳入标准。我们的研究结果显示有135名女性受访者和69名男性受访者。有趣的是，脾切除术与SCD患者生活质量的各个方面差异无显著关联。然而，数据显示接受胆囊切除术和髋关节置换术的患者在身体健康（p=0.002和p=0.022）和总体生活质量（p=0.024和p=0.042）方面的各自平均得分显著较低。相比之下，肩关节置换术似乎与身体健康（T=-2.597；p=0.010）和生活质量的环境方面（T=-2.016；p=0.045）的平均得分显著较低有关。
胆囊切除术、髋关节置换术和肩关节置换术与SCD患者较低的生活质量显著相关。
