Imamura Y, Kojima Y, Otagiri M
J Pharmacobiodyn. 1986 Jan;9(1):110-1. doi: 10.1248/bpb1978.9.110.
The acetohexamide reducing activity of cytosol of rabbit heart was compared with that of rabbit liver or kidney. The heart exhibited an approximately 2-fold higher activity than either the liver or kidney. Both aldehyde and ketone reductases may contribute to the reduction of acetohexamide by cytosol of rabbit heart. It is noteworthy that the heart is an important organ reducing acetohexamide.
将兔心脏胞质溶胶的醋磺己脲还原活性与兔肝脏或肾脏的进行比较。心脏的活性比肝脏或肾脏的活性高约2倍。醛还原酶和酮还原酶都可能参与兔心脏胞质溶胶对醋磺己脲的还原作用。值得注意的是，心脏是还原醋磺己脲的重要器官。
