The Centre for Regenerative Medicine and Devices, University of Brighton, UK.
J Wound Care. 2022 Mar 2;31(3):236-242. doi: 10.12968/jowc.2022.31.3.236.
Exudate is a vital component of healing wounds. There are differences between acute and chronic exudate, with the latter seen as highly toxic to the healing environment. Wound exudate assessment is not easy for clinicians. The viscosity of wound fluid/exudate is as important as its quantity. Wound fluid viscosity increases when it contains more protein. As wound dressings exhibit a variety of fluid-handling mechanisms, it is important to understand how they interact with the different exudate types, which may alter the wound/dressing interface. This knowledge will ensure a healing wound environment that is beneficial, not one that leaves harmful exudate on the wound surface. This study aimed to evaluate if the viscosity of exudate affected absorption time in four wound dressing types.
This study evaluated the viscosities of two solutions and their effect on the absorption times of four dressing types. The viscosities of the solutions were calculated using Ostwald viscometers, then 2 ml of each of these liquids was applied to each of the four dressing types and repeated 10 times for each dressing, as per British Standards Institution requirements. The parameters for temperature and frequency were applied, and the absorption times recorded. A two-way repeated analysis of variance (ANOVA) was conducted to examine if exudate viscosity and dressing type, or their interaction, affected the absorption time.
The results indicated that the viscosity of the solution alone had a significant effect on absorption time (p<0.01), and that the combined effect of dressing type and viscosity also affected absorption (p<0.01). The type of dressing alone was found to have a significant effect on absorption time (p<0.01). When looking at the between-subject effects of the dressings (between the four types) the only non-significant finding was between two dressings-the superabsorbent and the moderate (foam) absorbing dressing (p=0.097). All other dressings had a between-subject effect of (p<0.01).
A significant difference in absorption times was found in this investigation of dressing types and viscosity of test solutions. The greater the viscosity of the fluid, the longer it took for it to be absorbed into all dressing types tested. This delay was not determined simply by the dressing or by the viscosity of the fluid, but likely to be a combination of the mode of action of the dressing, its pore size and particulate composition of the exudate, all of which require further investigation.
渗出物是伤口愈合的重要组成部分。急性渗出物和慢性渗出物之间存在差异，后者被认为对愈合环境具有高度毒性。临床医生很难评估伤口渗出物。伤口流体/渗出物的粘度与其数量同样重要。当伤口流体含有更多蛋白质时，其粘度会增加。由于伤口敷料表现出多种流体处理机制，因此了解它们如何与不同的渗出物类型相互作用非常重要，这可能会改变伤口/敷料界面。这种知识将确保伤口愈合环境是有益的，而不是在伤口表面留下有害的渗出物。本研究旨在评估渗出物的粘度是否会影响四种伤口敷料类型的吸收时间。
本研究评估了两种溶液的粘度及其对四种敷料类型吸收时间的影响。使用奥斯特瓦尔德粘度计计算溶液的粘度，然后将每种溶液的 2 毫升分别应用于四种敷料类型，每种敷料重复 10 次，符合英国标准协会的要求。应用温度和频率参数，并记录吸收时间。进行了双因素重复方差分析（ANOVA），以检查渗出物粘度和敷料类型，或它们的相互作用是否影响吸收时间。
结果表明，单独的溶液粘度对吸收时间有显著影响（p<0.01），并且敷料类型和粘度的组合效应对吸收也有影响（p<0.01）。单独的敷料类型对吸收时间有显著影响（p<0.01）。当观察敷料的受试者间效应（四种类型之间）时，唯一没有显著差异的是两种敷料-超强吸收剂和中等（泡沫）吸收剂（p=0.097）。所有其他敷料都有受试者间效应（p<0.01）。
在对测试溶液的敷料类型和粘度的研究中发现吸收时间存在显著差异。流体的粘度越大，其被吸收到所有测试的敷料类型中所需的时间就越长。这种延迟不是由敷料或流体的粘度决定的，而是可能是敷料作用模式、其孔径和渗出物的颗粒组成的组合，所有这些都需要进一步研究。
