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英国唇腭裂患儿的现行外科治疗方法。

Current Surgical Practice for Children Born with a Cleft lip and/or Palate in the United Kingdom.

机构信息

The Cleft Collective, University of Bristol, Bristol, UK.

South West Cleft Service, University Hospital Bristol and Weston, Bristol, UK.

出版信息

Cleft Palate Craniofac J. 2023 Jun;60(6):679-688. doi: 10.1177/10556656221078151. Epub 2022 Feb 24.

Abstract

OBJECTIVE

This study describes primary surgical reconstructions performed for children born with a cleft lip and/or palate (CL ± P) in the United Kingdom (UK).

DESIGN

Data forms completed at the time of surgery included details on timing, technique, and adjuncts used during the operative period. Demographic data on participants were validated via parental questionnaires.

SETTING

Data were obtained from the Cleft Collective, a national longitudinal cohort study.

PATIENTS

Between 2015 and 2021, 1782 Cleft Collective surgical forms were included, relating to the primary reconstructions of 1514 individual children.

RESULTS

The median age at primary cheiloplasty was 4.3 months. Unilateral cleft lips (UCL) were reconstructed with an anatomical subunit approximation technique in 53%, whereas bilateral cleft lips (BCL) were reconstructed with a broader range of eponymous techniques. Clefts of the soft palate were reconstructed at a median age of 10.3 months with an intravelar veloplasty in 94% cases. Clefts of the hard palate were reconstructed with a vomer flap in 84% cases in a bimodal age distribution, relating to reconstruction carried out simultaneously with either lip or soft palate reconstruction. Antibiotics were used in 96% of cases, with an at-induction-only regimen used more commonly for cheiloplasties ( < .001) and a 5 to 7-day postoperative regime used more commonly for soft palatoplasties ( < .001). Perioperative steroids were used more commonly in palatoplasties than cheiloplasties ( < .001) but tranexamic acid use was equivalent ( = .73).

CONCLUSIONS

This study contributes to our understanding of current cleft surgical pathways in the UK and will provide a baseline for analysis of the effectiveness of utilized protocols.

摘要

目的

本研究描述了英国(UK)出生的唇裂和/或腭裂(CL ± P)患儿的初次手术重建情况。

设计

手术时填写的数据表包括手术期间的时间安排、技术和辅助手段的详细信息。通过家长问卷调查验证了参与者的人口统计学数据。

设置

数据来自全国性纵向队列研究 Cleft Collective。

患者

2015 年至 2021 年期间,共有 1782 份 Cleft Collective 手术表格纳入研究,涉及 1514 名患儿的初次重建手术。

结果

初次唇裂修复术的中位年龄为 4.3 个月。53%的单侧唇裂(UCL)采用解剖亚单位近似技术重建,而双侧唇裂(BCL)采用多种命名技术重建。软腭裂的中位修复年龄为 10.3 个月,94%的病例采用内收式咽成形术。硬腭裂采用双瓣法重建,84%的病例呈双峰分布,与同期行唇裂或软腭裂重建有关。96%的病例使用抗生素,唇裂修复术更常采用诱导时单次给药方案( < .001),软腭裂修复术更常采用 5-7 天术后给药方案( < .001)。围手术期类固醇在腭裂修复术中的使用更为常见,而在唇裂修复术中使用较少( < .001),但氨甲环酸的使用相当( = .73)。

结论

本研究有助于我们了解英国当前的唇腭裂手术途径,并为分析所采用方案的有效性提供基线数据。

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