Fell Matthew, Chong David, Parmar Paras, Su Ting-Li, Enocson Lars, Richard Bruce
Spires Cleft Centre, Oxford, UK.
The Cleft Collective, Bristol Dental School, University of Bristol, Bristol, UK.
Cleft Palate Craniofac J. 2025 Jun;62(6):1068-1073. doi: 10.1177/10556656241233220. Epub 2024 Feb 12.
ObjectiveTo determine whether facial growth at five years is different for children with a left versus right sided cleft lip and palate.DesignRetrospective cohort study.SettingSeven UK regional cleft centres.PatientsPatients born between 2000-2014 with a complete unilateral cleft lip and palate (UCLP).Main Outcomes Measure5-Year-Old's Index scores.Results378 children were included. 256 (68%) had a left sided UCLP and 122 (32%) had a right sided UCLP. 5-Year-Old's index scores ranged from 1 (good) to 5 (poor). There was a higher proportion of patients getting good scores (1 and 2) in left UCLP (43%) compared to right UCLP (37%) but there was weak evidence for a difference (Adjusted summary odds ratio 1.27, 95% CI 0.87 to 1.87; = .22).ConclusionsWhilst maxillary growth may be different for left versus right sided UCLP, definitive analysis requires older growth indices and arch forms.
目的
确定左侧唇腭裂与右侧唇腭裂患儿五岁时的面部生长情况是否存在差异。
设计
回顾性队列研究。
地点
英国七个地区性腭裂治疗中心。
患者
2000年至2014年间出生的单侧完全性唇腭裂（UCLP）患者。
主要观察指标
五岁儿童指数评分。
结果
共纳入378名儿童。其中256名（68%）为左侧UCLP，122名（32%）为右侧UCLP。五岁儿童指数评分范围为1（良好）至5（较差）。左侧UCLP患者获得良好评分（1分和2分）的比例（43%）高于右侧UCLP患者（37%），但差异证据不足（校正后汇总比值比为1.27，95%置信区间为0.87至1.87；P = 0.22）。
结论
虽然左侧与右侧UCLP的上颌生长情况可能存在差异，但明确的分析需要更长期的生长指标和牙弓形态。
