尼泊尔一家三级护理医院皮肤科门诊患者活检样本中的皮肤肿瘤：一项描述性横断面研究。

Skin Tumors among Biopsy Samples in Patients Attending Dermatological Out Patient Department in a Tertiary Care Hospital of Nepal: A Descriptive Cross-sectional Study.

机构信息

Department of Dermatology, Nepal Medical College and Teaching Hospital, Jorpati, Kathmandu, Nepal.

Nepal Medical College and Teaching Hospital, Jorpati, Kathmandu, Nepal.

出版信息

JNMA J Nepal Med Assoc. 2021 Sep 11;59(241):886-891. doi: 10.31729/jnma.6955.

DOI:10.31729/jnma.6955

PMID:35199716

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9107892/

Abstract

INTRODUCTION

Skin tumors are on the rise in the Nepalese community. The different morphological pattern of skin tumors requires its meticulous categorization for understanding its effect on prognosis and treatment. Our study aimed at studying the prevalence of skin tumors among the skin biopsies performed in the dermatology outpatient department in a tertiary care hospital of Nepal.

METHODS

A descriptive cross-sectional study was done from skin biopsy samples from 1st January, 2017 to 31st December, 2019, at a tertiary care center. Ethical clearance was taken from the institutional review committee (IRC), Ref No: 056-077/078. Convenience sampling was done. A self-designed proforma containing questions on the patients' socio-demographic data and clinical details were used, and a biopsy of those clinically suspected to have skin tumors was done. Skin tumors were classified according to the World Health Organization 2018 classification of skin tumors. Data were analyzed using Statistical Package for the Social Sciences Version 16. Point estimate at 95% Confidence Interval was done, and frequency and proportion were calculated.

RESULTS

A total of 671 skin biopsies were done during this study, out of which 125 (18.63%) at 95% Confidence Interval (15.68-21.57) were diagnosed with skin tumors. Among them, 77 (61.6%) were female, and 48 (38.4%) were male. Among the diagnosed cases, 105 (84%) were benign, and 20 (16%) were malignant. Females showed preponderance in both benign and malignant tumors.

CONCLUSIONS

The findings from our study show the increasing prevalence of skin tumors, and the results were comparable to other similar studies conducted in various parts of Nepal.

摘要

简介

尼泊尔社区的皮肤肿瘤发病率正在上升。不同形态的皮肤肿瘤需要进行细致的分类，以了解其对预后和治疗的影响。我们的研究旨在研究尼泊尔一家三级保健医院皮肤科门诊进行的皮肤活检中皮肤肿瘤的患病率。

方法

这是一项描述性的横断面研究，从 2017 年 1 月 1 日至 2019 年 12 月 31 日在一家三级保健中心进行的皮肤活检样本中进行。已从机构审查委员会（IRC）获得伦理批准，编号为 056-077/078。采用方便抽样法。使用包含患者社会人口统计学数据和临床详细信息问题的自行设计的表格，对那些临床上怀疑患有皮肤肿瘤的患者进行活检。皮肤肿瘤根据 2018 年世界卫生组织皮肤肿瘤分类进行分类。使用社会科学统计软件包 16 版进行数据分析。在 95%置信区间（15.68-21.57）进行点估计，并计算频率和比例。

结果

在这项研究中，共进行了 671 次皮肤活检，其中 125 次（18.63%）在 95%置信区间（15.68-21.57）中被诊断为皮肤肿瘤。其中，77 例（61.6%）为女性，48 例（38.4%）为男性。在诊断出的病例中，105 例（84%）为良性，20 例（16%）为恶性。女性在良性和恶性肿瘤中均占优势。