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产科急性肾损伤患者在三级医院的肾功能完全恢复:描述性横断面研究。

Complete Recovery of Renal Function among Obstetric Patients with Acute Kidney Injury at a Tertiary Care Hospital: A Descriptive Cross-sectional Study.

机构信息

Department of Obstetrics and Gynaecology, Nobel Medical College and Teaching Hospital, Biratnagar, Nepal.

Department of Nephrology, Nobel Medical College and Teaching Hospital, Biratnagar, Nepal.

出版信息

JNMA J Nepal Med Assoc. 2021 Dec 11;59(244):1289-1292. doi: 10.31729/jnma.7135.

Abstract

INTRODUCTION

Acute kidney injury  is a rare complication of pregnancy and is associated with high maternal morbidity and mortality. Obstetric factors associated with it are preeclampsia/eclampsia, sepsis, hemorrhage and dehydration. Here, we aim to find out the prevalence of complete recovery of renal function among obstetric patients with acute kidney injury.

METHODS

This is a descriptive cross-sectional study conducted in a tertiary care hospital from 1st July 2020 to 30th June 2021 where obstetric patients who had developed acute kidney injury were included and followed till 6 weeks of diagnosis. Ethical approval was obtained from Institutional Review Committee of Nobel Medical College and Teaching Hospital (IRC- NMCTH 437/2020). The convenience sampling method was used. Data entry and analysis were done using Statistical Package for Social Sciences version 21. Point estimate at 95% Confidence Interval was calculated along with frequency and proportion for binary data.

RESULTS

Out of total 66 obstetric patients with acute kidney injury, 45 (68.2%) (57-79.3 at 95% Confidence Interval) had complete recovery of renal function. Rate of renal function recovery in Stage 1, Stage 2 and Stage 3 acute kidney injury were 19 (90%), 19 (86%) and 7 (58%) respectively. The most common causes of acute kidney injury were Preeclampsia/eclampsia 18 (40%), sepsis 23 (28.8%) and hemorrhage 10 (22.2%).

CONCLUSIONS

The prevalence of complete recovery in obstetric patients with acute kidney injury was similar to findings from other studies done in similar settings.

摘要

简介

急性肾损伤是妊娠的罕见并发症,与母体发病率和死亡率高有关。与之相关的产科因素有子痫前期/子痫、败血症、出血和脱水。在这里,我们旨在找出产科急性肾损伤患者肾功能完全恢复的患病率。

方法

这是一项在 2020 年 7 月 1 日至 2021 年 6 月 30 日期间在一家三级保健医院进行的描述性横断面研究,其中纳入了发生急性肾损伤的产科患者,并在诊断后随访 6 周。伦理批准获得诺贝尔医学院和教学医院机构审查委员会(IRC-NMCTH 437/2020)。使用便利抽样法。使用社会科学统计软件包 21 版进行数据录入和分析。计算了 95%置信区间的点估计值,以及二项数据的频率和比例。

结果

在总共 66 例产科急性肾损伤患者中,45 例(68.2%)(95%置信区间为 57-79.3)肾功能完全恢复。急性肾损伤 1 期、2 期和 3 期的肾功能恢复率分别为 19 例(90%)、19 例(86%)和 7 例(58%)。急性肾损伤的最常见原因是子痫前期/子痫 18 例(40%)、败血症 23 例(28.8%)和出血 10 例(22.2%)。

结论

在产科急性肾损伤患者中,完全恢复的患病率与在类似环境中进行的其他研究的发现相似。

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