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年轻男性和女性雄激素受体基因多态性、攻击性与社会地位之间的关系

The Relationship between Androgen Receptor Gene Polymorphism, Aggression and Social Status in Young Men and Women.

作者信息

Valenzuela Nohelia T, Ruiz-Pérez Irene, Rodríguez-Sickert Carlos, Polo Pablo, Muñoz-Reyes José Antonio, Yeste-Lizán Ali, Pita Miguel

机构信息

Laboratorio de Comportamiento Animal y Humano, Centro de Investigación en Complejidad Social, Facultad de Gobierno, Universidad del Desarrollo, Las Condes 7590943, Chile.

Departamento de Biología, Facultad de Ciencias, Universidad Autónoma de Madrid, 28049 Madrid, Spain.

出版信息

Behav Sci (Basel). 2022 Feb 10;12(2):42. doi: 10.3390/bs12020042.

Abstract

In both sexes, aggression has been described as a critical trait to acquire social status. Still, almost uniquely in men, the link between aggressiveness and the genetic background of testosterone sensitivity measured from the polymorphism in the androgen receptor () gene has been previously investigated. We assessed the relevance of the gene to understand aggression and how aggressiveness affects social status in a cross-sectional study of 195 participants, for the first time in both young men and women. We estimated polymorphism sequences from saliva and measured aggression and self-perceived social status. Unfortunately, the results did not support our prediction because we did not find any of the expected relationships. Therefore, the results suggest that the genetic association between aggressive mechanisms and polymorphism of the gene is less straightforward than expected, at least in men, and seems to indicate that aggression is not usually used to gain social status in our population.

摘要

在两性中,攻击性都被描述为获得社会地位的关键特质。然而,几乎只有男性的攻击性与通过雄激素受体()基因多态性测得的睾酮敏感性遗传背景之间的联系此前得到过研究。我们在一项针对195名参与者的横断面研究中,首次对年轻男性和女性进行评估,以了解雄激素受体基因与攻击性的相关性,以及攻击性如何影响社会地位。我们从唾液中估计多态性序列,并测量攻击性和自我感知的社会地位。遗憾的是,结果并不支持我们的预测,因为我们没有发现任何预期的关系。因此,结果表明,至少在男性中,攻击机制与雄激素受体基因多态性之间的遗传关联比预期的要复杂,这似乎表明在我们的人群中,攻击性通常并非用于获取社会地位。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79ac/8869512/cdf052d413ad/behavsci-12-00042-g001.jpg

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