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双侧弥漫性葡萄膜黑素细胞增生症最初表现为青光眼。

Bilateral Diffuse Uveal Melanocytic Proliferation Initially Presented as Glaucoma.

机构信息

Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin, China.

出版信息

Ocul Immunol Inflamm. 2023 Apr;31(3):601-608. doi: 10.1080/09273948.2022.2032201. Epub 2022 Feb 24.

Abstract

PURPOSE

To report a bilateral diffuse uveal melanocytic proliferation (BDUMP) patient whose initial presentation was glaucoma.

METHODS

Clinical review of a BDUMP case.

RESULTS

A 65-year-old woman presented with ocular pain of the left eye for 1 day and vision loss of the right eye for 1 week. An ophthalmological examination revealed increased intraocularr pressure in the left eye and shallow anterior chamber in both eyes. BDUMP was diagnosed following a series of auxiliary examinations. After 1.5 years of follow-up, progressive cataracts appeared, and the patient accepted cataract surgery in both eyes. Visual acuity improved from light perception to 20/100 in both eyes 1.5 years after cataract surgery, but declined to light perception again at the last follow-up.

CONCLUSION

BDUMP can be initially presented as glaucoma, and cataract surgery can be considered in BDUMP patients in order to improve the patients' quality of life, even if exudative retinal detachment exists.

摘要

目的

报告 1 例以青光眼为首发表现的双侧弥漫性葡萄膜黑色素细胞增生(BDUMP)患者。

方法

对 1 例 BDUMP 病例进行临床回顾。

结果

1 例 65 岁女性,左眼眼部疼痛 1 天,右眼视力丧失 1 周。眼科检查发现左眼眼内压升高,双眼前房变浅。经过一系列辅助检查,诊断为 BDUMP。随访 1.5 年后,出现进行性白内障,患者双眼均接受白内障手术。白内障手术后 1.5 年,双眼视力从光感提高到 20/100,但在最后一次随访时再次降至光感。

结论

BDUMP 可初诊为青光眼,即使存在渗出性视网膜脱离,也可考虑对 BDUMP 患者行白内障手术以提高患者的生活质量。

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