Girolamo Nicola Di, Caron Marianne, Brandão João, Reynders Reint Meursinge
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK.
Department of Oral and Maxillofacial Surgery, Amsterdam University Medical Center (Amsterdam UMC) Location AMC, Meibergdreef 9, Amsterdam, Netherlands.
J Am Vet Med Assoc. 2022 Feb 24;260(8):1-11. doi: 10.2460/javma.21.03.0116.
To assess what information sources veterinarians use to select drug dosages for treating exotic animals and how they implement this information.
936 veterinarians from Europe, Asia, Australia, Africa, and the Americas.
An anonymous, online survey was used to collect data on information sources used for dosage decisions by veterinarians treating exotic species. Logistic regression models were built to identify associations between individual characteristics and primary outcomes.
Respondents reported their single most common source for establishing drug dosages as formularies (682/936 [72.9%]), followed by scientific journals (96 [10.3%]), other textbooks (68 [7.3%]), colleagues (47 [5.0%]), or continuing education notes (38 [4.1%]). Over two-thirds of the respondents (645, 68.9%) consulted a specific exotic animal formulary for establishing drug dosages in most situations. Of the 936 respondents, 407 (43.5%) reported that they sometimes (318 [34.0%]) or never (89 [9.5%]) checked the source of a dosage in a textbook or a formulary, 503 (55.3%) reported that they sometimes (399 [42.6%]) or never (104 [11.1%]) searched the original publication on a dosage, and 486 (51.9%) reported that they would base their dosage decision on the abstract of an article if they had no access to the full-text. Several respondents' reported characteristics were significant predictors of primary outcomes.
Considering our findings, we recommend authors of formularies and textbooks should focus on evidence-based information and state clearly when information is anecdotal. Tailored strategies to educate veterinarians treating exotic animals on the importance of primary sources are also recommended.
评估兽医在选择用于治疗外来动物的药物剂量时使用哪些信息来源，以及他们如何运用这些信息。
来自欧洲、亚洲、澳大利亚、非洲和美洲的936名兽医。
采用匿名在线调查收集治疗外来物种的兽医在剂量决策时所使用信息来源的数据。构建逻辑回归模型以确定个体特征与主要结果之间的关联。
受访者表示确定药物剂量最常用的单一来源是处方集（682/936 [72.9%]），其次是科学期刊（96 [10.3%]）、其他教科书（68 [7.3%]）、同事（47 [5.0%]）或继续教育笔记（38 [4.1%]）。超过三分之二的受访者（645，68.9%）在大多数情况下会参考特定的外来动物处方集来确定药物剂量。在936名受访者中，407人（43.5%）表示他们有时（318 [34.0%]）或从不（89 [9.5%]）核对教科书或处方集中剂量的来源，503人（55.3%）表示他们有时（399 [42.6%]）或从不（104 [11.1%]）查找剂量的原始文献，486人（51.9%）表示如果无法获取全文，他们会根据文章摘要做出剂量决定。几位受访者报告的特征是主要结果的显著预测因素。
鉴于我们的研究结果，我们建议处方集和教科书的作者应注重基于证据的信息，并在信息为轶事性时明确说明。还建议制定针对性策略，对外来动物治疗兽医开展关于原始资料重要性的教育。
