Barton Amy E, Borchard Gerrit, Wacker Matthias G, Pastorin Giorgia, Saleem Imran Y, Chaudary Shaqil, Elbayoumi Tamer, Zhao Zhigang, Flühmann Beat
Vifor Pharma Group, Vifor Pharma Management Ltd., Flughofstrasse 61, 8152 Glattbrugg, Switzerland.
Section of Pharmaceutical Sciences, School of Pharmaceutical Sciences of Western Switzerland (ISPSO), University of Geneva,1, Rue Michel Servet, 1211 Geneva, Switzerland.
Pharmacy (Basel). 2022 Jan 21;10(1):17. doi: 10.3390/pharmacy10010017.
The emerging landscape of nanomedicine includes a wide variety of active pharmaceutical ingredients and drug formulations. Their design provides nanomedicines with unique features leading to improved pharmacokinetics and pharmacodynamics. They are manufactured using conventional or biotechnological manufacturing processes. Their physical characteristics are vastly different from traditional small-molecule drugs. Pharmacists are important members of the multi-disciplinary team of scientists involved in their development and clinical application. Consequently, their training should lead to an understanding of the complexities associated with the production and evaluation of nanomedicines. Therefore, student pharmacists, post-doctoral researchers, and trainees should be given more exposure to this rapidly evolving class of therapeutics. This commentary will provide an overview of nanomedicine education within the selection of pharmacy programs globally, discuss the current regulatory challenges, and describe different approaches to incorporate nanomedicine science in pharmacy programs around the world.
纳米医学的新兴领域包括各种各样的活性药物成分和药物制剂。它们的设计赋予纳米药物独特的特性,从而改善药代动力学和药效学。它们采用传统或生物技术制造工艺生产。其物理特性与传统小分子药物有很大不同。药剂师是参与其研发和临床应用的多学科科学家团队的重要成员。因此,对他们的培训应使他们了解与纳米药物生产和评估相关的复杂性。所以,药学专业学生、博士后研究人员和实习生应更多地接触这类快速发展的治疗方法。本评论将概述全球药学专业课程中纳米医学教育的情况,讨论当前的监管挑战,并描述将纳米医学科学纳入世界各地药学专业课程的不同方法。