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婴儿后期年龄与阶段问卷对 5 岁时低平均认知能力的预测价值。

The predictive value of the ages and stages questionnaire in late infancy for low average cognitive ability at age 5.

机构信息

INFANT Research Centre, Paediatric Academic Unit, Cork University Hospital, Cork, Ireland.

Department of Paediatrics, School of Medicine, University College Cork, Cork, Ireland.

出版信息

Acta Paediatr. 2022 Jun;111(6):1194-1200. doi: 10.1111/apa.16309. Epub 2022 Mar 3.

Abstract

AIM

This retrospective, longitudinal study examined the predictive value of the ages and stages questionnaire (ASQ) in late infancy for identifying children who progressed to have low cognitive ability at 5 years of age.

METHODS

The ASQ was performed on 755 participants from the Irish BASELINE birth cohort at 24 or 27 months of age. Intelligence quotient was measured at age 5 with the Kaufmann Brief Intelligence Test, Second Edition, and low cognitive ability was defined as a score more than 1 standard deviation below the mean. The ASQ's predictive value was examined, together with other factors associated with low cognitive ability at 5 years.

RESULTS

When the ASQ was performed at 24 or 27 months, the overall sensitivity for identifying low cognitive ability at 5 years was 20.8% and the specificity was 91.1%. Using a total score cut-off point increased the sensitivity to 46.6% and 71.4% at 24 and 27 months, but specificity fell to 74.1% and 67.2%, respectively. After adjusting for ASQ performance, maternal education and family income were strongly associated with cognitive outcomes at 5 years.

CONCLUSION

The ASQ did not detect the majority of children with low cognitive ability at age 5. Alternative methods need investigation.

摘要

目的

本回顾性纵向研究旨在探讨年龄与阶段问卷(ASQ)在婴儿晚期的预测价值,以识别出在 5 岁时认知能力较低的儿童。

方法

在爱尔兰 BASELINE 出生队列中,755 名参与者在 24 或 27 个月时接受了 ASQ 测试。在 5 岁时使用 Kaufmann 简明智能测试第二版测量智商,低认知能力定义为得分低于平均值 1 个标准差以上。同时还检查了 ASQ 的预测价值,以及与 5 岁时认知能力较低相关的其他因素。

结果

当在 24 或 27 个月时进行 ASQ 测试时,识别 5 岁时认知能力较低的整体敏感性为 20.8%,特异性为 91.1%。使用总分截断值可将敏感性分别提高到 24 个月时的 46.6%和 27 个月时的 71.4%,但特异性分别降至 74.1%和 67.2%。在调整了 ASQ 表现后,母亲教育程度和家庭收入与 5 岁时的认知结果密切相关。

结论

ASQ 并未检测到大多数在 5 岁时认知能力较低的儿童。需要研究替代方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6a7c/9314849/1fd6cd546273/APA-111-1194-g001.jpg

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