Opitz Marcel, Zensen Sebastian, Breuckmann Katharina, Bos Denise, Forsting Michael, Hoffmann Oliver, Stuschke Martin, Wetter Axel, Guberina Nika
Institute of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, 45147 Essen, Germany.
Department of Obstetrics and Gynecology, University Hospital Essen, 45147 Essen, Germany.
Diagnostics (Basel). 2022 Feb 10;12(2):456. doi: 10.3390/diagnostics12020456.
According to a position paper of the European Commission Initiative on Breast Cancer (ECIBC), DBT is close to being introduced in European breast cancer screening programmes. Our study aimed to examine radiation dose delivered by digital breast tomosynthesis (DBT) and digital mammography (FFDM) in comparison to sole FFDM in a clinical follow-up setting and in an identical patient cohort. Retrospectively, 768 breast examinations of 96 patients were included. Patients received both DBT and FFDM between May 2015 and July 2019: FFDM in cranio-caudal (CC) and DBT in mediolateral oblique (MLO) view, as well as a follow-up examination with FFDM in CC and MLO view. The mean glandular dose (MGD) was determined by the mammography system according to Dance's model. The MGD (standard deviation (SD), interquartile range (IQR)) was distributed as follows: (CC+MLO) left FFDM 1.40 mGy (0.36 mGy, 1.13-1.59 mGy), left DBT 1.62 mGy (0.51 mGy, 1.27-1.82 mGy); right FFDM 1.36 mGy (0.34 mGy, 1.14-1.51 mGy), right DBT 1.59 mGy (0.52 mGy, 1.27-1.62 mGy). (CC+MLO) left FFDM 1.35 mGy (0.35 mGy, 1.10-1.60 mGy), left FFDM 1.40 mGy (0.39 mGy, 1.12-1.59 mGy), right FFDM 1.35 mGy (0.33 mGy, 1.12-1.48 mGy), right FFDM 1.40 mGy (0.36 mGy, 1.14-1.58 mGy). MGD was significantly higher for DBT mlo views compared to FFDM ( < 0.001). Radiation dose was significantly higher for DBT in MLO views compared to FFDM. However, the MGD of DBT MLO lies below the national diagnostic reference level of 2 mGy for an FFDM view. Hence, our results support the use of either DBT or FFDM as suggested in the ECIBC's Guidelines.
根据欧盟委员会乳腺癌倡议（ECIBC）的一份立场文件，数字乳腺断层合成（DBT）即将被引入欧洲乳腺癌筛查项目。我们的研究旨在比较数字乳腺断层合成（DBT）和数字乳腺钼靶（FFDM）与单纯FFDM在临床随访环境和相同患者队列中的辐射剂量。回顾性地纳入了96例患者的768次乳腺检查。患者在2015年5月至2019年7月期间接受了DBT和FFDM检查：头尾位（CC）的FFDM检查和内外斜位（MLO）的DBT检查，以及CC和MLO位的FFDM随访检查。平均腺体剂量（MGD）由乳腺钼靶系统根据丹斯模型确定。MGD（标准差（SD），四分位数间距（IQR））分布如下：（CC + MLO）左侧FFDM为1.40 mGy（0.36 mGy，1.13 - 1.59 mGy），左侧DBT为1.62 mGy（0.51 mGy，1.27 - 1.82 mGy）；右侧FFDM为1.36 mGy（0.34 mGy，1.14 - 1.51 mGy），右侧DBT为1.59 mGy（0.52 mGy，1.27 - 1.62 mGy）。（CC + MLO）左侧FFDM为1.35 mGy（0.35 mGy，1.10 - 1.60 mGy），左侧FFDM为1.40 mGy（0.39 mGy，1.12 - 1.59 mGy），右侧FFDM为1.35 mGy（0.33 mGy，1.12 - 1.48 mGy），右侧FFDM为1.40 mGy（0.36 mGy，1.14 - 1.58 mGy）。与FFDM相比，DBT的MLO位视图的MGD显著更高（<0.001）。与FFDM相比，DBT在MLO位视图中的辐射剂量显著更高。然而，DBT MLO的MGD低于FFDM视图2 mGy的国家诊断参考水平。因此，我们的结果支持按照ECIBC指南的建议使用DBT或FFDM。
