Institut des Maladies Neurodégénératives, UMR 5293, Université de Bordeaux, 33076 Bordeaux, France.
CNRS, Institut des Maladies Neurodégénératives, UMR 5293, 33076 Bordeaux, France.
Biomolecules. 2022 Jan 28;12(2):228. doi: 10.3390/biom12020228.
While confronted with the increasing complexity of the neurobiology of Parkinson's disease (PD), we face the ever-increasing sloppiness of the conceptual definitions associated with poor methodological characterizations and the use of unacknowledged proxies, all of which are harmful contributors to the overall slow progress of PD research. In this opinion paper, I share part of my frustration, acknowledge how I participate in this trend, and propose a simple remedy. Fighting against semantic or conceptual sloppiness is of paramount importance, notably for the benefit of newcomers to the field who otherwise would take for granted the classic assertions found in the literature.
面对帕金森病（PD）神经生物学日益复杂的局面，我们面临着与之相关的概念定义越来越不精确的问题，这些定义方法描述欠佳，而且使用了未经承认的替代指标，所有这些都是导致 PD 研究进展缓慢的有害因素。在这篇观点文章中，我分享了部分自己的挫败感，承认了我如何参与这一趋势，并提出了一个简单的补救措施。与语义或概念上的含糊不清作斗争至关重要，特别是对于该领域的新手而言，否则他们会想当然地认为文献中存在经典论断。
