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基于格子玻尔兹曼方法的房间隔缺损下心内血流模拟

Simulation of Cardiac Flow under the Septal Defect Based on Lattice Boltzmann Method.

作者信息

Wang Zhengdao, Zhang Xiandong, Li Yumeng, Yang Hui, Xue Haihong, Wei Yikun, Qian Yuehong

机构信息

State-Province Joint Engineering Lab of Fluid Transmission System Technology, Faculty of Mechanical Engineering and Automation, Zhejiang Sci-Tech University, Hangzhou 310018, China.

Department of Pediatric, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200092, China.

出版信息

Entropy (Basel). 2022 Jan 27;24(2):187. doi: 10.3390/e24020187.

DOI:10.3390/e24020187
PMID:35205482
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8871033/
Abstract

In this paper, the lattice Boltzmann method was used to simulate the cardiac flow in children with aseptal defect. The inner wall model of the heart was reconstructed from 210 computed tomography scans. By simulating and comparing the cardiac flow field, the pressure field, the blood oxygen content, and the distribution of entropy generation before and after an operation, the effects of septal defect on pulmonary hypertension(PH), cyanosis, and heart load were analyzed in detail. It is found that the atrial septal defect(ASD) of the child we analyzed had a great influence on the blood oxygen content in the pulmonary artery, which leads to lower efficiency of oxygen binding in the lungs and increases the burden on the heart. At the same time, it also significantly enhanced the entropy generation rate of the cardiac flow, which also leads to a higher heart load. However, the main cause of PH is not ASD, but ventricular septal defect (VSD). Meanwhile, it significantly reduced the blood oxygen content in the brachiocephalic trunk, but rarely affects the blood oxygen contents in the downstream left common carotid artery, left subclavian artery, and descending aorta are not significantly affected by VSD. It causes severe cyanosis on the face and lips.

摘要

在本文中，采用格子玻尔兹曼方法模拟了患有房间隔缺损儿童的心脏血流。心脏内壁模型由210例计算机断层扫描重建而成。通过模拟和比较手术前后的心脏流场、压力场、血氧含量和熵产生分布，详细分析了房间隔缺损对肺动脉高压（PH）、紫绀和心脏负荷的影响。研究发现，我们分析的儿童房间隔缺损（ASD）对肺动脉中的血氧含量有很大影响，这导致肺部氧结合效率降低，并增加心脏负担。同时，它还显著提高了心脏血流的熵产生率，这也导致更高的心脏负荷。然而，PH的主要原因不是ASD，而是室间隔缺损（VSD）。同时，它显著降低了头臂干中的血氧含量，但很少影响下游左颈总动脉、左锁骨下动脉中的血氧含量，降主动脉受VSD影响不显著。它会导致面部和嘴唇出现严重紫绀。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1476/8871033/00c9063ba3c0/entropy-24-00187-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1476/8871033/ef9712280ae1/entropy-24-00187-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1476/8871033/857c2a470792/entropy-24-00187-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1476/8871033/8924059ba4ed/entropy-24-00187-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1476/8871033/00c9063ba3c0/entropy-24-00187-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1476/8871033/ef9712280ae1/entropy-24-00187-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1476/8871033/36439362ad14/entropy-24-00187-g002.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1476/8871033/691b3781478a/entropy-24-00187-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1476/8871033/3932987dd74b/entropy-24-00187-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1476/8871033/9e25d0dcc95c/entropy-24-00187-g006a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1476/8871033/857c2a470792/entropy-24-00187-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1476/8871033/8924059ba4ed/entropy-24-00187-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1476/8871033/00c9063ba3c0/entropy-24-00187-g009.jpg

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本文引用的文献

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Comput Math Methods Med. 2021 Apr 1;2021:2618625. doi: 10.1155/2021/2618625. eCollection 2021.
2
Medical Image-Based Hemodynamic Analyses in a Study of the Pulmonary Artery in Children With Pulmonary Hypertension Related to Congenital Heart Disease.基于医学影像的血流动力学分析在先天性心脏病相关肺动脉高压患儿肺动脉研究中的应用
Front Pediatr. 2020 Dec 2;8:521936. doi: 10.3389/fped.2020.521936. eCollection 2020.
3
Pulmonary hypertension associated with congenital heart disease; clinical decision scenario.
先天性心脏病相关肺动脉高压；临床决策案例
Respir Med Case Rep. 2020 Nov 11;31:101286. doi: 10.1016/j.rmcr.2020.101286. eCollection 2020.
4
Time Evolution Features of Entropy Generation Rate in Turbulent Rayleigh-Bénard Convection with Mixed Insulating and Conducting Boundary Conditions.具有混合绝缘和传导边界条件的湍流瑞利-贝纳德对流中熵产生率的时间演化特征
Entropy (Basel). 2020 Jun 17;22(6):672. doi: 10.3390/e22060672.
5
Non-invasive Prediction of Peak Systolic Pressure Drop across Coarctation of Aorta using Computational Fluid Dynamics.使用计算流体动力学对主动脉缩窄处收缩压峰值下降进行无创预测。
Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul;2020:2295-2298. doi: 10.1109/EMBC44109.2020.9176461.
6
Computational fluid dynamics: a primer for congenital heart disease clinicians.计算流体动力学：先天性心脏病临床医生入门指南。
Asian Cardiovasc Thorac Ann. 2020 Oct;28(8):520-532. doi: 10.1177/0218492320957163. Epub 2020 Sep 2.
7
4D flow MRI applications in congenital heart disease.4D 血流磁共振成像在先天性心脏病中的应用。
Eur Radiol. 2021 Feb;31(2):1160-1174. doi: 10.1007/s00330-020-07210-z. Epub 2020 Sep 1.
8
Emerging 3D technologies and applications within congenital heart disease: teach, predict, plan and guide.新兴的 3D 技术及其在先天性心脏病中的应用：教学、预测、规划和指导。
Future Cardiol. 2020 Nov;16(6):695-709. doi: 10.2217/fca-2020-0004. Epub 2020 Jul 6.
9
Assessment of right ventricular function in patients with pulmonary arterial hypertension-congenital heart disease and repaired and unrepaired defects: Correlation among speckle tracking, conventional echocardiography, and clinical parameters.肺动脉高压-先天性心脏病并修复和未修复缺陷患者右心室功能评估：斑点追踪、传统超声心动图和临床参数的相关性。
Anatol J Cardiol. 2020 Apr;23(5):277-287. doi: 10.14744/AnatolJCardiol.2020.01379.
10
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Radiol Med. 2019 Dec;124(12):1238-1252. doi: 10.1007/s11547-019-01097-7. Epub 2019 Oct 19.