Field E J, Shenton V K, Jenssen H L, Keöhler H, Günther J K
Zh Mikrobiol Epidemiol Immunobiol. 1978 Mar(3):70-5.
A test of measurement of the electrophoretic mobility of macrophages (EMM) is used for detection of the product secreted by the sensitized lymphocytes after the contact with the antigen. Thus, by reduction of the macrophage mobility it is possible to assess the sensitization level of the lymphocyte population under study. This offers a possibility of using this test for the diagnosis of some infectious diseases, for provisional diagnosis of malignant growth, and also of destructive affections of the nervous system. The EMM test finds wide application in the determination of compatibility of donor's and the recipient's tissues before the transplantation, and also to assess the efficacy of immunodepressive therapy.
巨噬细胞电泳迁移率(EMM)测定试验用于检测致敏淋巴细胞与抗原接触后分泌的产物。因此,通过降低巨噬细胞迁移率,可以评估所研究淋巴细胞群体的致敏水平。这为将该试验用于某些传染病的诊断、恶性肿瘤的初步诊断以及神经系统的破坏性病变提供了可能性。EMM试验在移植前供体和受体组织相容性的测定中得到广泛应用,也用于评估免疫抑制治疗的疗效。