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预测甲状腺相关性眼病联合眼眶减压术和斜视手术成功率的因素

Factors Predicting the Success of Combined Orbital Decompression and Strabismus Surgery in Thyroid-Associated Orbitopathy.

作者信息

Hsieh Meng-Wei, Hsu Chih-Kang, Kuo Pao-Cheng, Chang Hsu-Chieh, Chen Yi-Hao, Chien Ke-Hung

机构信息

Department of Ophthalmology, Taoyuan Armed Forces General Hospital, Taoyuan 325, Taiwan.

Department of Ophthalmology, Tri-Service General Hospital Songshan Branch, Songshan, Taipei 105, Taiwan.

出版信息

J Pers Med. 2022 Jan 31;12(2):186. doi: 10.3390/jpm12020186.

Abstract

To evaluate the safety and efficacy of orbital decompression combined with strabismus surgery in thyroid-associated orbitopathy (TAO) and identify factors leading to surgical success. A retrospective comparative case series was conducted on 52 patients who were treated with combined orbital decompression and strabismus surgery. Outcome measurements included perioperative Hertel exophthalmometry and strabismus measurements. Surgical success was defined as binocular single vision (BSV) in the primary and reading positions within 5 prism diopters (PDs). As a result, the average reduction in proptosis was 3.23 mm, with a mean preoperative Hertel measurement of 22.64 mm. Forty-four patients (84.6%) achieved the success criterion and composed the success group. In addition to sex and underlying hyperthyroidism, symmetry of orbitopathy, interocular exophthalmos difference of more than 2 mm, predominant esotropia type, mixed type strabismus, baseline horizontal deviations, baseline vertical deviations, and combination with one-wall decompression surgery were significantly different between the success and failure groups. All complications were mild and temporary. Orbital decompression combined with strabismus surgery produced satisfactory outcomes in selected patients with efficacy and safety. Symmetry between the two eyes with relatively simple strabismus and proptosis ensured surgical success. With experienced surgeons, advanced techniques, and selected patients, this method can serve as an alternative treatment option to minimize the number of surgeries, medical costs and recovery period.

摘要

评估眼眶减压联合斜视手术治疗甲状腺相关眼病(TAO)的安全性和有效性,并确定导致手术成功的因素。对52例行眼眶减压联合斜视手术的患者进行回顾性比较病例系列研究。结果测量包括围手术期Hertel眼球突出度测量和斜视测量。手术成功定义为在5棱镜度(PD)范围内,第一眼位和阅读眼位达到双眼单视(BSV)。结果,眼球突出平均减少3.23mm,术前Hertel测量平均值为22.64mm。44例患者(84.6%)达到成功标准,组成成功组。除性别和潜在的甲状腺功能亢进外,成功组和失败组在眼眶病对称性、两眼间眼球突出度差异大于2mm、主要内斜视类型、混合型斜视、基线水平偏差、基线垂直偏差以及与单壁减压手术联合方面存在显著差异。所有并发症均为轻度且为暂时性。眼眶减压联合斜视手术在部分患者中产生了令人满意的疗效和安全性。两眼对称性、斜视和眼球突出相对简单确保了手术成功。有经验的外科医生、先进的技术以及合适的患者,这种方法可作为一种替代治疗选择,以减少手术次数、医疗费用和恢复期。

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