Mazzucchi Giulia, Lollobrigida Marco, Lamazza Luca, Serafini Giorgio, Di Nardo Dario, Testarelli Luca, De Biase Alberto
Department of Oral and Maxillofacial Sciences, Sapienza University of Rome, 00161 Rome, Italy.
Materials (Basel). 2022 Feb 15;15(4):1431. doi: 10.3390/ma15041431.
This preliminary study aims to evaluate the efficacy of an autologous dentin graft in preventing periodontal defects after impacted or semi-impacted lower third molars' (M3) surgical extraction. For this purpose, radiographic and periodontal evaluation of post-extractive sockets were performed. Ten patients were enrolled in the study: twenty M3 extraction sockets were treated with a split-mouth modality. After tooth extraction, the experimental sites were filled with autologous dentin graft obtained by the extracted M3, while the control sites were filled with blood clot alone. Flaps were closed by first intention to ensure the stability of the wounds. Post-extractive sites were monitored at days 15, 90 and 180. The healing was not affected by any complications associated with the use of the autologous dentine graft in all cases. The measurements recorded at six months showed a reduction of the probing pocket depth distal to the second lower molar (M2) at both surgical sites, with a greater reduction observed at the experimental sites. Radiographic evaluation also showed a greater amount of bone gain at the grafted sites compared to the control sites. The results of this preliminary study suggest that autologous dentin grafts can be useful in preventing the formation of periodontal defects distal to M2 after M3 surgical extraction.
这项初步研究旨在评估自体牙本质移植物在预防阻生或半阻生下颌第三磨牙（M3）手术拔除后牙周缺损方面的疗效。为此，对拔牙后的牙槽窝进行了影像学和牙周评估。该研究纳入了10名患者：采用双侧对照的方式对20个M3拔牙窝进行治疗。拔牙后，实验组牙槽窝填充由拔除的M3获取的自体牙本质移植物，而对照组牙槽窝仅填充血凝块。创口一期缝合以确保伤口稳定。在术后第15天、90天和180天对拔牙后的创口进行监测。在所有病例中，愈合均未受到与使用自体牙本质移植物相关的任何并发症的影响。六个月时记录的测量结果显示，两个手术部位下颌第二磨牙（M2）远中探诊深度均减小，且实验组减小幅度更大。影像学评估还显示，与对照组相比，移植部位的骨增量更多。这项初步研究的结果表明，自体牙本质移植物在预防M3手术拔除后M2远中牙周缺损的形成方面可能有用。
