Burghouts J, Haanen C
Scand J Haematol. 1986 Apr;36(4):376-8. doi: 10.1111/j.1600-0609.1986.tb01752.x.
The remission duration (RD) of 22 adult acute myelogenous leukaemia patients who received maintenance rifampicin treatment during 24 episodes was significantly longer than RD in 29 complete remission patients who received conventional maintenance chemotherapy (25 versus 9 months, p less than 0.003). Although this study was not randomized, the observed RD in the rifampicin group suggests a suppressive activity upon regrowth of residual disease in acute myelogenous leukaemia during apparent complete remission.
22例在24个疗程中接受利福平维持治疗的成年急性髓性白血病患者的缓解持续时间（RD）显著长于29例接受传统维持化疗的完全缓解患者（分别为25个月和9个月，p<0.003）。尽管这项研究并非随机对照研究，但利福平组观察到的缓解持续时间表明，在急性髓性白血病明显完全缓解期间，利福平对残留疾病的复发具有抑制作用。
