Guelpa G, Trono D, Audetat F, Hochstrasser D
Schweiz Med Wochenschr. 1986 May 10;116(19):647-51.
The syndrome of thrombotic thrombocytopenic purpura (TTP) has an uncertain course, is often fatal, and its pathogenesis is obscure. None of the treatments suggested is of proven efficacy. Two cases of TTP are reported with a favourable outcome probably due to continuous intravenous perfusion of prostacyclin combined with antiplatelet drugs for several days, after steroids, plasmapheresis and fresh plasma had failed. The two patients are at present in complete remission after 8 and 20 months under prophylactic treatment with salicylate and dipyridamole.
血栓性血小板减少性紫癜（TTP）综合征病程不确定，常危及生命，其发病机制不明。所建议的治疗方法均未证实有效。本文报告两例TTP患者，在使用类固醇、血浆置换和新鲜血浆治疗无效后，通过持续静脉输注前列环素并联合抗血小板药物治疗数天，获得了良好疗效。目前，这两名患者在使用水杨酸盐和双嘧达莫进行预防性治疗8个月和20个月后，已完全缓解。
