新型冠状病毒肺炎感染的新生儿。
Coronavirus Disease 2019 Infection in Newborns.
机构信息
Division of Newborn, Weill Cornell Medicine, 1283 York Avenue, New York, NY 10065, USA.
Division of Pediatric Infectious Diseases, Weill Cornell Medicine- New York Presbyterian Hospital, 505 East 70th Street, New York, NY 10065, USA.
出版信息
Clin Perinatol. 2022 Mar;49(1):73-92. doi: 10.1016/j.clp.2021.11.005. Epub 2021 Nov 9.
Abstract
Maternal severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can present with or without symptoms at the time of birth. Symptomatic mothers are more likely be associated with preterm births. Population studies demonstrate a consistent association of SARS-CoV-2 infection and a reduction in preterm birth rate. Newborns with positive SARS-CoV-2 test results appear to have minimal burden of illness that is directly associated with a viral infection. Neonatal mortality directly related to SARS-CoV-2 is extremely rare. Maternal vaccination in pregnant women leads to maternal antibody production, and this can occur as early as 5 days after the first vaccination dose.
摘要
母亲严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）感染在出生时可能出现症状或无症状。有症状的母亲更可能与早产有关。人群研究表明，SARS-CoV-2 感染与早产率降低之间存在一致的关联。SARS-CoV-2 检测结果呈阳性的新生儿的疾病负担似乎很小，这与病毒感染直接相关。与 SARS-CoV-2 直接相关的新生儿死亡率极其罕见。孕妇接种疫苗可导致母体抗体产生，这最早可在第一剂疫苗接种后 5 天发生。
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