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通过磁共振成像检测到的复发性多软骨炎患者的咽鼓管受累:病例报告

Eustachian tube involvement in a patient with relapsing polychondritis detected by magnetic resonance imaging: A case report.

作者信息

Yunaiyama Daisuke, Aoki Akiko, Kobayashi Hiroshi, Someya Miwako, Okubo Mitsuru, Saito Kazuhiro

机构信息

Department of Radiology, Tokyo Medical University Hospital, Shinjuku-ku 160-0023, Tokyo, Japan.

Department of Rheumatology, Tokyo Medical University Hachioji Medical Center, Hachioji-shi 193-0998, Japan.

出版信息

World J Clin Cases. 2022 Feb 6;10(4):1441-1446. doi: 10.12998/wjcc.v10.i4.1441.

DOI:10.12998/wjcc.v10.i4.1441
PMID:35211581
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8855176/
Abstract

BACKGROUND

Relapsing polychondritis (RP) is a rare inflammatory disease involving the systemic cartilage, such as the auricle, trachea, and bronchiole, among others. A patient with RP shows variable symptoms based on the involved cartilage.

CASE SUMMARY

A 72-year-old Japanese woman with a history of redness of the bilateral auricles for 3 d was referred to a clinician. The clinician prescribed antibiotics to the patient; however, the symptoms worsened; thus, she was referred to our hospital. Head and neck magnetic resonance imaging (MRI) showed edematous auricle with remarkable contrast, fluid collection in the bilateral mastoid cells, suggesting otitis media. The eustachian tube (ET) on the right side was also edematous with contrast enhancement. The patient was suspected of RP according to the diagnostic criteria. A biopsy of the auricular cartilage was performed by an otorhinolaryngologist, confirming pathological proof of RP. Treatments with steroids were immediately administered thereafter.

CONCLUSION

We highlight a rare case of RP with radiologically confirmed involvement of ET in the MRI.

摘要

背景

复发性多软骨炎(RP)是一种罕见的累及全身软骨的炎症性疾病,如耳廓、气管和细支气管等。RP患者根据受累软骨表现出不同的症状。

病例摘要

一名72岁有双侧耳廓发红3天病史的日本女性被转诊至一名临床医生处。临床医生给患者开了抗生素;然而,症状恶化;因此,她被转诊至我院。头颈部磁共振成像(MRI)显示耳廓水肿且有明显强化,双侧乳突气房有积液,提示中耳炎。右侧咽鼓管(ET)也有水肿并伴有强化。根据诊断标准,该患者被怀疑为RP。一名耳鼻喉科医生对耳廓软骨进行了活检,证实了RP的病理证据。此后立即给予类固醇治疗。

结论

我们重点介绍了一例罕见的RP病例,MRI显示放射学证实ET受累。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/526e/8855176/49f390ddc4b1/WJCC-10-1441-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/526e/8855176/38c3e7cb9db0/WJCC-10-1441-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/526e/8855176/49f390ddc4b1/WJCC-10-1441-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/526e/8855176/38c3e7cb9db0/WJCC-10-1441-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/526e/8855176/49f390ddc4b1/WJCC-10-1441-g002.jpg

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本文引用的文献

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Characteristics and Clinical Outcomes of 295 Patients With Relapsing Polychondritis.295例复发性多软骨炎患者的特征及临床结局
J Rheumatol. 2021 Dec;48(12):1876-1882. doi: 10.3899/jrheum.210062. Epub 2021 Aug 1.
2
Relapsing polychondritis patients were divided into three subgroups: patients with respiratory involvement (R subgroup), patients with auricular involvement (A subgroup), and overlapping patients with both involvements (O subgroup), and each group had distinctive clinical characteristics.复发性多软骨炎患者被分为三个亚组:有呼吸道受累的患者(R亚组)、有耳部受累的患者(A亚组)以及同时有两种受累情况的重叠患者(O亚组),且每组都有独特的临床特征。
Medicine (Baltimore). 2018 Oct;97(42):e12837. doi: 10.1097/MD.0000000000012837.
3
Refractory relapsing polychondritis: challenges and solutions.难治性复发性多软骨炎:挑战与解决方案
Open Access Rheumatol. 2018 Jan 9;10:1-11. doi: 10.2147/OARRR.S142892. eCollection 2018.
4
Relapsing Polychondritis Can Be Characterized by Three Different Clinical Phenotypes: Analysis of a Recent Series of 142 Patients.复发性多软骨炎可表现为三种不同的临床表型:对最近的 142 例患者系列的分析。
Arthritis Rheumatol. 2016 Dec;68(12):2992-3001. doi: 10.1002/art.39790.
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Clinical and prognostic characteristics of 158 cases of relapsing polychondritis in China and review of the literature.158例中国复发性多软骨炎患者的临床及预后特征并文献复习
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Imaging diagnosis in relapsing polychondritis and correlation with clinical and serological data.复发性多软骨炎的影像学诊断及其与临床和血清学数据的相关性
Skeletal Radiol. 2016 Mar;45(3):339-46. doi: 10.1007/s00256-015-2270-x.
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Orbital Relapsing Polychondritis: A Unique Presentation, Complication, and Treatment.眼眶复发性多软骨炎:一种独特的表现、并发症及治疗方法。
Ophthalmic Plast Reconstr Surg. 2016 Mar-Apr;32(2):e34-6. doi: 10.1097/IOP.0000000000000222.
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Otologic manifestations of relapsing polychondritis. Review of literature and report of nine cases.
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Relapsing polychondritis.复发性多软骨炎
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