Elsass P
Acta Neurol Scand. 1986 Mar;73(3):225-46. doi: 10.1111/j.1600-0404.1986.tb03269.x.
The Continuous Reaction Times (CRT) method was used to examine pharmacological, psychiatric, medical and neurological problems in clinical practice where a detailed neuropsychological examination with a test battery was not possible. Either 100 visual or 150 auditory stimuli were given within a period of 6 1/2 or 10 min respectively, and the patients were instructed to react as quickly as possible to every stimulus. The same CRT method was applied to heterogeneous groups of patients with cerebral dysfunction and control subjects. The results demonstrated that it was useful as a screening test for the presence of cerebral dysfunction and was especially sensitive to progressive diseases. Its discriminative power was equivalent to more sophisticated and complex psychological tests. Even if CRT is a valid and reliable method of testing cerebral affection, the neural background for the reaction time process is still unknown and the test did not distinguish between patients with right- or left-hemisphere lesions and was not influenced by the etiology of the disease. CRT is therefore considered a provisional method, suggestive only for the actual diagnostic procedures. Only when the patients have a well-defined diagnosis e.g. a diffuse cerebral affection caused by a drug or a metabolic disorder can CRT be recommended as a measure of the degree of lowered consciousness.
连续反应时间（CRT）方法用于临床实践中检查药理学、精神病学、医学和神经学问题，此时无法使用一套测试进行详细的神经心理学检查。分别在6.5分钟或10分钟内给予100个视觉刺激或150个听觉刺激，并指示患者对每个刺激尽快做出反应。相同的CRT方法应用于脑功能障碍患者的异质群体和对照受试者。结果表明，它作为脑功能障碍存在的筛查测试是有用的，并且对进行性疾病特别敏感。其鉴别能力等同于更复杂的心理测试。即使CRT是检测脑病变的有效且可靠的方法，但反应时间过程的神经背景仍然未知，该测试无法区分右半球或左半球病变的患者，也不受疾病病因的影响。因此，CRT被认为是一种临时方法，仅对实际诊断程序具有提示作用。只有当患者有明确诊断时，例如由药物或代谢紊乱引起的弥漫性脑病变，CRT才能被推荐作为意识降低程度的一种测量方法。
