Department of Surgery, Minimally Invasive Surgery Research Center, Division of Minimally Invasive and Bariatric Surgery, Rasool-E Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
Center of Excellence of European Branch of International Federation for Surgery of Obesity, Hazrat_e Rasool Hospital, Tehran, Iran.
Obes Surg. 2022 May;32(5):1726-1733. doi: 10.1007/s11695-022-05980-7. Epub 2022 Feb 24.
This systematic review and meta-analysis intend to evaluate the efficacy of metabolic/bariatric surgeries (MBS) in patients with type-1 diabetes mellitus. A systematic literature search and meta-analysis were performed in electronic databases up to July 2021. In total, 27 primary studies comprising 648 subjects were included in this systematic review and meta-analysis. Patients had a mean age of 38.0 ± 7.3 years. Preoperative mean BMI was 42.6 ± 4.7 kg/m and 29.4 ± 4.7 kg/m after surgery, respectively. Following bariatric surgeries in patients with type 1 diabetes mellitus, insulin (unit/day) decreased by a weighted mean difference (WMD) of - 10.59. Also, insulin (unit/kg/day) decreased by a WMD of - 0.2, and HbA1C decreased by a WMD of - 0.71, showing MBS acceptable and durable effects of bariatric surgical procedures.
本系统评价和荟萃分析旨在评估代谢/减重手术（MBS）在 1 型糖尿病患者中的疗效。我们对电子数据库进行了系统的文献检索和荟萃分析，检索时间截至 2021 年 7 月。本系统评价和荟萃分析共纳入 27 项原始研究，共 648 例患者。患者的平均年龄为 38.0±7.3 岁。术前平均 BMI 为 42.6±4.7kg/m，术后分别为 29.4±4.7kg/m。1 型糖尿病患者接受减重手术后，胰岛素（单位/天）的平均差值（WMD）减少了 10.59。此外，胰岛素（单位/千克/天）的 WMD 减少了 0.2，HbA1C 的 WMD 减少了 0.71，表明 MBS 具有可接受和持久的减重手术效果。
