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单吻合口胃旁路术转为 Roux-en-Y 胃旁路术:一项回顾性多中心研究的结果。

Conversion of One Anastomosis Gastric Bypass to Roux-en-Y Gastric Bypass: Results of a Retrospective Multicenter Study.

机构信息

Service de Chirurgie Digestive, Oesogastrique Et Bariatrique, Hôpital Bichat Claude Bernard, APHP 7, 75018, Paris, France.

Université de Paris, Inserm UMR 1149, 75018, Paris, France.

出版信息

Obes Surg. 2022 Jun;32(6):1842-1848. doi: 10.1007/s11695-022-05963-8. Epub 2022 Feb 25.

Abstract

BACKGROUND

One anastomosis gastric bypass (OAGB) may expose the patient to certain specific complications. Here, we report the results of conversion of OAGB to Roux-en-Y gastric bypass (RYGB) in terms of outcomes and weight loss.

METHODS

Between January 2009 and January 2019, all patients undergoing conversion of OAGB to RYGB because of complications due to OAGB (n = 23) were included. The primary efficacy endpoint was the effectiveness of converting OAGB to RYGB. The secondary endpoints were overall mortality and morbidity during the first 3 postoperative months, specific morbidity, reoperation, length of hospitalization, weight loss, and progression of comorbidities related to obesity at 2-year follow-up.

RESULTS

Indications for conversion were bile reflux (n = 14; 60.9%), severe malnutrition (n = 3; 13%), gastro-gastric fistula (n = 4; 17.4%), and anastomotic leak (n = 2; 8.7%). The median time interval between OAGB and conversion to RYGB was 34 months (0-158). At the time of RYGB, median body mass index (BMI) was 28.0 kg/m (18.2-50.7), representing a median BMI change of 14.0 (- 1.7-43.5). Fifteen surgeries (65.1%) were completed laparoscopically. Five complications (21.7%) were recorded, including 2 major ones (8.7%). Reoperation rate was 4.3% (n = 1). At 24 months of follow-up (n = 18; 78.3%), median BMI was 28.7 kg/m (19.4-35.4), representing a median BMI change of 19.5 (12.2-43.1). No patient complained of bile reflux or persistent malnutrition.

CONCLUSION

RYGB performed as revisional surgery for complications after OAGB is an effective procedure with no major weight regain at 2 years of follow-up.

摘要

背景

单吻合口胃旁路术(OAGB)可能使患者面临某些特定的并发症。在此,我们报告了因 OAGB 相关并发症而将 OAGB 转为 Roux-en-Y 胃旁路术(RYGB)的结果,包括疗效和减重效果。

方法

2009 年 1 月至 2019 年 1 月期间,因 OAGB 相关并发症而行 OAGB 转为 RYGB 的所有患者(n=23)均被纳入研究。主要疗效终点是 OAGB 转为 RYGB 的效果。次要终点是术后 3 个月内的总死亡率和发病率、具体发病率、再次手术、住院时间、体重减轻以及 2 年随访时与肥胖相关的合并症进展情况。

结果

转为 RYGB 的指征包括胆汁反流(n=14,占 60.9%)、严重营养不良(n=3,占 13%)、胃-胃吻合口瘘(n=4,占 17.4%)和吻合口漏(n=2,占 8.7%)。OAGB 转为 RYGB 的中位时间间隔为 34 个月(0-158 个月)。行 RYGB 时,中位 BMI 为 28.0kg/m²(18.2-50.7kg/m²),代表 BMI 平均降低 14.0kg/m²(-1.7-43.5kg/m²)。15 例手术(65.1%)经腹腔镜完成。记录到 5 例(21.7%)并发症,包括 2 例(8.7%)重大并发症。再次手术率为 4.3%(n=1)。24 个月随访时(n=18,占 78.3%),中位 BMI 为 28.7kg/m²(19.4-35.4kg/m²),代表 BMI 平均降低 19.5kg/m²(12.2-43.1kg/m²)。无患者抱怨胆汁反流或持续营养不良。

结论

OAGB 术后并发症行 RYGB 翻修术是一种有效的手术,2 年随访时无明显体重反弹。

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