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实施血库生成管进行第二血型鉴定:挑战、产量和成本。

Implementation of a blood bank generated tube for second blood group determination: Challenges, yield, and cost.

机构信息

Department of Medicine, University of Toronto, Toronto, Ontario, Canada.

Division of Transfusion Medicine and Tissue Bank, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.

出版信息

Transfusion. 2022 Apr;62(4):784-790. doi: 10.1111/trf.16838. Epub 2022 Feb 25.

DOI:10.1111/trf.16838
PMID:35213739
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9304256/
Abstract

BACKGROUND

The second blood group determination or group check sample is a process of verifying the ABO group with a second blood sample prior to transfusion. It has been used to detect errors related to wrong blood in tube (WBIT) events and reduce the risk of ABO-incompatible transfusions. To prevent the clinical team from collecting the group check sample at the same time as the first sample, a tan top tube only available from the blood bank was introduced for second blood group determinations if drawn within 24 h of the first group and screen.

STUDY DESIGN AND METHODS

This is a retrospective study analyzing data from 2005 to 2020 before and after the implementation of the blood bank supplied tan top tube for group check. The number of WBIT events, transfusion delays, and health care costs were determined.

RESULTS

The number of WBIT events remained unchanged throughout the time period. No delays in transfusion or procedure were reported due to the tan top tube group check. There was no increase in group O transfusions over time. In comparison to using an ethylenediaminetetraacetic acid (EDTA) tube, the tan top tube was estimated to add an extra yearly cost of $790.79 Canadian dollars.

CONCLUSION

Second blood group determination using the blood bank supplied tan top tube did not increase the number of WBIT events detected but ensured an independent sample draw. A minimal incremental cost of implementing the tan top tube was noted with no delay in transfusions or procedures.

摘要

背景

第二次血型确定或血型复查样本是在输血前用第二份血样来验证 ABO 血型的过程。它被用于检测与错管血(WBIT)事件相关的错误,并降低 ABO 不相容输血的风险。为了防止临床团队在采集第一份样本的同时采集血型复查样本,引入了一种仅在血库提供的棕红色顶部采血管,用于在第一次血型和筛查后的 24 小时内进行第二次血型确定。

研究设计和方法

这是一项回顾性研究,分析了 2005 年至 2020 年在实施血库提供的棕红色顶部采血管进行血型复查前后的数据。确定了 WBIT 事件、输血延迟和医疗保健成本的数量。

结果

在整个时间段内,WBIT 事件的数量保持不变。由于棕红色顶部采血管的血型复查,没有报告输血或程序延迟。随着时间的推移,O 型血的输血并没有增加。与使用乙二胺四乙酸(EDTA)管相比,棕红色顶部采血管估计每年增加 790.79 加元的额外成本。

结论

使用血库提供的棕红色顶部采血管进行第二次血型确定并没有增加检测到的 WBIT 事件的数量,但确保了独立的样本采集。实施棕红色顶部采血管的增量成本很小,输血或程序没有延迟。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3db7/9304256/e148ffca5b29/TRF-62-784-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3db7/9304256/50909bd493f9/TRF-62-784-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3db7/9304256/e148ffca5b29/TRF-62-784-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3db7/9304256/50909bd493f9/TRF-62-784-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3db7/9304256/e148ffca5b29/TRF-62-784-g002.jpg

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Factors associated with wrong blood in tube errors: An international case series - The BEST collaborative study.与管内血错误相关的因素:一项国际病例系列研究——BEST 协作研究。
Transfusion. 2022 Jan;62(1):44-50. doi: 10.1111/trf.16716. Epub 2021 Nov 2.
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Electronic patient identification for sample labeling reduces wrong blood in tube errors.
电子病人标识用于样本标记可减少采血管错误。
Transfusion. 2019 Mar;59(3):972-980. doi: 10.1111/trf.15102. Epub 2018 Dec 14.
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BMJ Open Qual. 2018 Jul 15;7(3):e000270. doi: 10.1136/bmjoq-2017-000270. eCollection 2018.
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Transfusion. 2018 Jul;58(7):1697-1707. doi: 10.1111/trf.14608. Epub 2018 Apr 17.
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Arch Pathol Lab Med. 2017 Feb;141(2):255-259. doi: 10.5858/arpa.2016-0167-CP.
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Wrong blood in tube - potential for serious outcomes: can it be prevented?采血管内血液错误——存在严重后果的可能性:能否预防?
Br J Haematol. 2015 Jan;168(1):3-13. doi: 10.1111/bjh.13137. Epub 2014 Oct 4.
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