MacIvor Duncan, Triulzi Darrell J, Yazer Mark H
Department of Pathology, University of Pittsburgh, and The Institute for Transfusion Medicine, Pittsburgh, Pennsylvania, USA.
Transfusion. 2009 Jan;49(1):40-3. doi: 10.1111/j.1537-2995.2008.01923.x. Epub 2008 Sep 16.
Pittsburgh's Centralized Transfusion Service (CTS) provides transfusion support to 16 hospitals and features an electronic database that contains patient transfusion and serologic histories. This database can be accessed from any hospital in the system. A major cause of ABO-incompatible transfusions is the "wrong blood in tube" (WBIT) phenomenon, that is, the sample is not from the recipient identified on the label. We hypothesized that having access to patient historical ABO types from anywhere in the CTS system can identify WBIT errors and prevent mistransfusions.
The transfusion committee records of the 16 CTS hospitals from March 2005 to September 2007 were reviewed for major collection errors, that is, the current ABO type differed from the historical type in the database. The patient's historical ABO type, the discrepant type, and the hospital(s) where these samples were collected were recorded.
In 6 of 16 major collection errors for which complete information was available, the current and historical ABO types were obtained from different hospitals within the CTS system. In 3 cases, selection of ABO type-specific blood based on the current sample would have led to an ABO-compatible transfusion (e.g., correct type A, current type O). In the other 3 cases, an ABO-incompatible transfusion would have resulted (e.g., correct type O, current type A).
Access to a centralized patient database detected 38 percent more ABO typing errors and prevented six mistransfusions, which would not have been prevented at a single institution. Centralization of patient transfusion data should be encouraged.
匹兹堡的集中输血服务中心(CTS)为16家医院提供输血支持,并设有一个电子数据库,其中包含患者的输血和血清学病史。该数据库可从系统内的任何一家医院访问。ABO血型不匹配输血的一个主要原因是“管内血样错误”(WBIT)现象,即样本并非来自标签上所标识的受血者。我们推测,在CTS系统内的任何地方都能获取患者的历史ABO血型,这可以识别WBIT错误并防止误输血。
回顾了2005年3月至2007年9月期间16家CTS医院的输血委员会记录,以查找主要的采集错误,即当前的ABO血型与数据库中的历史血型不同。记录了患者的历史ABO血型、不一致的血型以及采集这些样本的医院。
在可获取完整信息的16例主要采集错误中,有6例的当前和历史ABO血型是从CTS系统内的不同医院获取的。在3例中,根据当前样本选择特定ABO血型的血液会导致ABO血型匹配的输血(例如,正确血型为A,当前血型为O)。在另外3例中,则会导致ABO血型不匹配的输血(例如,正确血型为O,当前血型为A)。
访问集中式患者数据库检测出的ABO血型鉴定错误多了38%,并防止了6次误输血,而这些在单个机构是无法预防的。应鼓励集中患者输血数据。