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高分辨率 3-D CZT 漂移条探测器在硼中子俘获治疗中用于瞬发伽马射线测量的潜力。

Potentialities of High-Resolution 3-D CZT Drift Strip Detectors for Prompt Gamma-Ray Measurements in BNCT.

机构信息

Department of Physics and Chemistry (DiFC)-Emilio Segrè, University of Palermo, Viale delle Scienze, Edificio 18, 90128 Palermo, Italy.

IMEM/CNR, Parco Area delle Scienze 37/A, 43100 Parma, Italy.

出版信息

Sensors (Basel). 2022 Feb 15;22(4):1502. doi: 10.3390/s22041502.

DOI:10.3390/s22041502
PMID:35214414
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8878856/
Abstract

Recently, new high-resolution cadmium-zinc-telluride (CZT) drift strip detectors for room temperature gamma-ray spectroscopic imaging were developed by our group. The CZT detectors equipped with orthogonal anode/cathode collecting strips, drift strips and dedicated pulse processing allow a detection area of 6 × 20 mm and excellent room temperature spectroscopic performance (0.82% FWHM at 661.7 keV). In this work, we investigated the potentialities of these detectors for prompt gamma-ray spectroscopy (PGS) in boron neutron capture therapy (BNCT). The detectors, exploiting the measurement of the 478 keV prompt gamma rays emitted by 94% Li nuclides from the B(n, α)Li reaction, are very appealing for the development of single-photon emission computed tomography (SPECT) systems and Compton cameras in BNCT. High-resolution gamma-ray spectra from B samples under thermal neutrons were measured at the T.R.I.G.A. Mark II research nuclear reactor of the University of Pavia (Italy).

摘要

最近,我们小组开发了用于室温下伽马射线光谱成像的新型高分辨率碲锌镉(CZT)漂移条探测器。这些 CZT 探测器配备正交的阳极/阴极收集条、漂移条和专用的脉冲处理,可实现 6×20mm 的探测面积和出色的室温光谱性能(在 661.7keV 处为 0.82%FWHM)。在这项工作中,我们研究了这些探测器在硼中子俘获治疗(BNCT)中的瞬发伽马射线光谱学(PGS)的潜力。探测器利用 B(n,α)Li 反应中 94%Li 核发射的 478keV 瞬发伽马射线进行测量,非常适合于在 BNCT 中开发单光子发射计算机断层扫描(SPECT)系统和康普顿相机。在意大利帕维亚大学的 T.R.I.G.A. Mark II 研究核反应堆中,对热中子下的 B 样品进行了高分辨率伽马射线光谱测量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a26/8878856/2b62483ca26c/sensors-22-01502-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a26/8878856/d0cdf4ec12ad/sensors-22-01502-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a26/8878856/abde2b8e0c75/sensors-22-01502-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a26/8878856/8b6c597d5d65/sensors-22-01502-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a26/8878856/9a7b1259f1a3/sensors-22-01502-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a26/8878856/7b82aed69600/sensors-22-01502-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a26/8878856/4f68b2cd72df/sensors-22-01502-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a26/8878856/2b62483ca26c/sensors-22-01502-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a26/8878856/d0cdf4ec12ad/sensors-22-01502-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a26/8878856/abde2b8e0c75/sensors-22-01502-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a26/8878856/8b6c597d5d65/sensors-22-01502-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a26/8878856/9a7b1259f1a3/sensors-22-01502-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a26/8878856/7b82aed69600/sensors-22-01502-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a26/8878856/4f68b2cd72df/sensors-22-01502-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a26/8878856/2b62483ca26c/sensors-22-01502-g007.jpg

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