Blythe J G
Am J Obstet Gynecol. 1978 Jun 15;131(4):438-45. doi: 10.1016/0002-9378(78)90420-9.
Radiation and gynecologic oncologists agree that pelvic irradiation in the presence of pelvic inflammatory disease, parametritis, or pyometra can be catastrophic. A temperature elevation in a patient having intrauterine radiation is very perplexing. This study was designed to investigate one of the three reported etiologies for this condition. Some investigators have suggested an exacerbation of a quiescent infection as a possible etiology because of the necrotic condition of many cancerous cervices. Aerobic, anaerobic, and fungus cultures were performed on 32 patients prior to intrauterine administration of cesium. The organisms cultured were similar to those identified as the normal cervical flora. The frequency of the organisms seemed independent of the amount of irradiation. The number of organisms cultured did not vary with the use or nonuse of cleansing vaginal suppositories. This study indicated no increase in bacterial growth in these cancerous necrotic cervices; also it did not indicate the growth of any unusual pathologic bacteria.
放射肿瘤学家和妇科肿瘤学家一致认为，在存在盆腔炎、子宫旁组织炎或积脓的情况下进行盆腔照射可能是灾难性的。接受子宫内放射治疗的患者体温升高是非常令人困惑的。本研究旨在调查针对这种情况所报道的三种病因之一。一些研究人员认为，由于许多癌性宫颈的坏死状况，静止感染的加剧可能是病因。在32名患者子宫内给予铯之前，进行了需氧菌、厌氧菌和真菌培养。培养出的微生物与被确定为正常宫颈菌群的微生物相似。这些微生物的出现频率似乎与照射量无关。培养出的微生物数量不因使用或不使用清洁阴道栓剂而有所不同。这项研究表明，这些癌性坏死宫颈中的细菌生长没有增加；也没有表明有任何异常病原菌生长。
