Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati College of Medicine, Cincinnati, USA.
Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, USA.
Int Forum Allergy Rhinol. 2022 Nov;12(11):1397-1412. doi: 10.1002/alr.22988. Epub 2022 Mar 9.
Acoustic energy and vibration therapy are emerging as helpful adjuncts among many disease states. There has been interest in how this technology can either serve as an alternative treatment or enhance delivery of medications to treat pathology within the nasal cavity and paranasal sinuses. Our objective was to perform a scoping review of the state of the science of vibration treatment used in sinonasal disease.
A search of Embase, PubMed, and CINAHL databases was performed in November 2021. Included studies evaluated acoustic energy as a means of treatment in sinonasal diseases. Data points collected included type of technology utilized, disease state treated, and outcomes.
The initial search identified 2902 studies, of which 44 met inclusion criteria. A wide array of vibrational technology such as ultrasound, sonic aerosols, and phonophoresis, with varying frequency and amplitude were described. Twenty-six studies evaluated the use of acoustic energy to treat sinonasal disease itself, while 18 studies evaluated the use of acoustic energy to facilitate drug delivery to the sinonasal cavity. Outcome measures among studies were highly varied.
Vibration technology used in patients with sinonasal pathology has been shown to improve pain, sinonasal symptoms, and radiologic outcome measures in small studies. Given the heterogeneous study populations and outcomes, no conclusion could be reached regarding overall effectiveness of acoustic energy as a primary treatment. Further research is required to study specific treatment indications in larger patient populations to fully understand the potential clinical benefit and to determine optimal therapeutic characteristics of sound energy.
声波能量和振动疗法在许多疾病状态下已成为有益的辅助治疗手段。人们对这项技术如何既能作为替代疗法，又能增强鼻腔和鼻窦内药物输送的效果产生了兴趣。我们的目的是对用于治疗鼻腔鼻窦疾病的振动治疗技术的现有科学研究进行范围界定综述。
于 2021 年 11 月对 Embase、PubMed 和 CINAHL 数据库进行了检索。纳入的研究评估了声波能量作为治疗鼻腔鼻窦疾病的一种手段。收集的数据点包括所使用的技术类型、治疗的疾病状态和结果。
最初的搜索确定了 2902 项研究，其中 44 项符合纳入标准。研究中描述了各种振动技术，如超声、声气溶胶和声透入，频率和幅度各不相同。26 项研究评估了声波能量在治疗鼻腔鼻窦疾病本身的应用，而 18 项研究评估了声波能量在促进药物输送到鼻腔鼻窦腔的应用。研究中的评估指标差异很大。
在患有鼻腔鼻窦病变的患者中使用振动技术已被证明可改善疼痛、鼻腔鼻窦症状和影像学结果，但在小型研究中。鉴于研究人群和结果存在异质性，不能得出关于声波能量作为主要治疗手段的总体有效性的结论。需要进一步的研究来在更大的患者群体中研究特定的治疗指征，以充分了解潜在的临床益处，并确定声音能量的最佳治疗特性。
