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后路颈椎减压融合术治疗脊髓病后,矢状位对线的改善与术后早期颈部残疾和与疼痛相关的患者报告结局相关。

Improved Sagittal Alignment Is Associated with Early Postoperative Neck Disability and Pain-Related Patient-Reported Outcomes Following Posterior Cervical Decompression and Fusion for Myelopathy.

机构信息

Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.

Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota, USA.

出版信息

World Neurosurg. 2022 May;161:e654-e663. doi: 10.1016/j.wneu.2022.02.075. Epub 2022 Feb 23.

DOI:10.1016/j.wneu.2022.02.075
PMID:35218962
Abstract

OBJECTIVE

To compare patient-reported outcomes measures (PROMs) following posterior cervical decompression and fusion (PCDF) based on changes in perioperative cervical sagittal alignment.

METHODS

We reviewed patients who underwent PCDF from C2 to T2 between the years 2015 and 2020. C2 sagittal vertical axis (SVA) and C2-C7 lordosis were assessed preoperatively and 1-year postoperatively. Neck Disability Index (NDI) and visual analog scale (VAS) Neck scores were collected preoperatively, 3 months' postoperatively, and 1-year postoperatively. PROMs were compared based on perioperative radiographic parameters.

RESULTS

Eighty-five patients were included in this study. Patients with preoperative C2 SVA <40 mm had a larger improvement in VAS Neck pain scores at 3 months' postoperatively (-4.9 vs. -3.0, P = 0.03) and a larger decrease in NDI scores at 1-year postoperatively (7.2 vs. 3.1, P = 0.04) than patients with C2 SVA ≥40 mm. Patients with postoperative C2 SVA <40 mm demonstrated lower VAS Neck pain scores at 3 months' postoperatively (2.0 vs. 3.4, P = 0.049). The cohort of patients with a decrease of C2 SVA by ≥5 mm demonstrated lower NDI at 3 months' postoperatively but not at 1-year postoperatively in comparison with patients whose C2 SVA increased or remained unchanged (11.7 vs. 23.8 vs. 18.2; P < 0.001). Patients in whom both C2 SVA and C2-C7 lordosis improved demonstrated superior NDI (P < 0.001) and VAS Neck (P = 0.007) at 3 months' but not at 1-year postoperatively.

CONCLUSIONS

In a uniform cohort of patients undergoing PCDF from C2 to T2, improvements in C2 SVA and C2-C7 lordosis were associated with improved early postoperative PROMs.

摘要

目的

比较基于围手术期颈椎矢状位alignment 变化的后路颈椎减压融合术(PCDF)后的患者报告结局测量(PROMs)。

方法

我们回顾了 2015 年至 2020 年间接受 C2 至 T2 段 PCDF 的患者。术前和术后 1 年评估 C2 矢状垂直轴(SVA)和 C2-C7 前凸。收集术前、术后 3 个月和术后 1 年的颈部残疾指数(NDI)和视觉模拟量表(VAS)颈部评分。根据围手术期影像学参数比较 PROMs。

结果

本研究纳入 85 例患者。术前 C2 SVA <40mm 的患者术后 3 个月 VAS 颈部疼痛评分改善更大(-4.9 比-3.0,P=0.03),术后 1 年 NDI 评分降低更大(7.2 比 3.1,P=0.04),C2 SVA ≥40mm 的患者。术后 C2 SVA <40mm 的患者术后 3 个月 VAS 颈部疼痛评分较低(2.0 比 3.4,P=0.049)。C2 SVA 降低≥5mm 的患者在术后 3 个月时 NDI 较低,但在术后 1 年时 NDI 与 C2 SVA 增加或保持不变的患者没有差异(11.7 比 23.8 比 18.2;P<0.001)。C2 SVA 和 C2-C7 前凸均改善的患者术后 3 个月时 NDI(P<0.001)和 VAS 颈部(P=0.007)改善更优,但术后 1 年时无差异。

结论

在接受 C2 至 T2 段 PCDF 的同质患者队列中,C2 SVA 和 C2-C7 前凸的改善与术后早期 PROMs 的改善相关。

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