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长期护理中的实用临床试验:与关键护理领域相关的研究挑战和潜在解决方案。

Pragmatic trials in long-term care: Research challenges and potential solutions in relation to key areas of care.

机构信息

University of Maryland School of Nursing, Baltimore, MD, USA.

Cecil G. Sheps Center for Health Services Research and Schools of Social Work and Pubic Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

出版信息

Geriatr Nurs. 2022 Mar-Apr;44:293-301. doi: 10.1016/j.gerinurse.2022.02.007. Epub 2022 Feb 24.

DOI:10.1016/j.gerinurse.2022.02.007
PMID:35219534
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9446463/
Abstract

As a method of research, pragmatic trials are recommended so as to generate results that are applicable to real-world care. This intent is especially important for the millions of older adults who receive long-term care in thousands of nursing homes and assisted living communities across the country-and many millions more around the globe. This article presents key points raised by experts participating in a conference funded by the National Institute of Aging held at the 2021 conference of the Society for Post-Acute and Long-term Care Medicine. The purpose of the conference was to convene leading clinicians, researchers, and industry partners to address special considerations of pragmatic trials in long-term care. Cross-cutting and unique challenges and solutions to conducting pragmatic trials were discussed focusing on 3 areas of clinical relevance to long-term care: (1) functional care and outcomes, (2) psychosocial care and quality of life, and (3) medical care and outcomes, with a special focus on persons with dementia. Challenges and innovative solutions were organized across the 9 domains of the revised Pragmatic-Explanatory Continuum Indicator Summary (PRECIS) Tool, and future research recommendations for pragmatic trials in long-term care were identified.

摘要

作为一种研究方法,建议采用实用临床试验,以产生适用于实际护理的结果。这对于在美国数以千计的养老院和辅助生活社区以及全球数以百万计的老年人接受长期护理的数百万人来说尤为重要。本文介绍了在国家老龄化研究所资助的会议上由参与会议的专家提出的要点,该会议是在长期护理医学协会 2021 年会议上举行的。会议的目的是召集领先的临床医生、研究人员和行业合作伙伴,以解决长期护理中实用临床试验的特殊考虑因素。讨论了贯穿性和独特的挑战和解决方案,重点关注长期护理的 3 个临床相关领域:(1)功能护理和结果,(2)心理社会护理和生活质量,(3)医疗护理和结果,特别关注痴呆症患者。根据修订后的实用-解释连续体指标总结(PRECIS)工具的 9 个领域组织了挑战和创新解决方案,并确定了长期护理中实用临床试验的未来研究建议。

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本文引用的文献

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Pragmatic Trials in Long-Term Care: Implementation and Dissemination Challenges and Opportunities.长期护理中的实用临床试验:实施和传播的挑战与机遇。
J Am Med Dir Assoc. 2022 Mar;23(3):339-344. doi: 10.1016/j.jamda.2021.11.024. Epub 2021 Dec 14.
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The Role of Implementation Science in Advancing Resource Generation for Health Interventions in Low- and Middle-Income Countries.实施科学在促进低收入和中等收入国家卫生干预措施资源生成中的作用。
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A New Care Model Reduces Polypharmacy and Potentially Inappropriate Medications in Long-Term Care.一种新的护理模式可减少长期护理中的药物滥用和潜在不适当用药。
J Am Med Dir Assoc. 2021 Jan;22(1):141-147. doi: 10.1016/j.jamda.2020.09.039. Epub 2020 Nov 19.
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Testing the Implementation of Function-focused Care in Assisted Living Settings.测试功能聚焦护理在辅助生活环境中的实施情况。
J Am Med Dir Assoc. 2021 Aug;22(8):1706-1713.e1. doi: 10.1016/j.jamda.2020.09.026. Epub 2020 Oct 31.
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Alternative Consent Models in Pragmatic Palliative Care Clinical Trials.实用主义姑息治疗临床试验中的替代同意模式。
J Pain Symptom Manage. 2021 Jul;62(1):183-191. doi: 10.1016/j.jpainsymman.2020.09.044. Epub 2020 Oct 29.
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"There is no one to pick up the pieces": Sustainability of antibiotic stewardship programs in nursing homes.“无人收拾残局”:养老院抗生素管理项目的可持续性。
Infect Control Hosp Epidemiol. 2021 Apr;42(4):440-447. doi: 10.1017/ice.2020.1217. Epub 2020 Oct 26.
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Implementation effectiveness of psychosocial and environmental care practices in assisted living.辅助生活中心理社会和环境关怀实践的实施效果。
Geriatr Nurs. 2021 Jan-Feb;42(1):295-302. doi: 10.1016/j.gerinurse.2020.09.003. Epub 2020 Oct 8.