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一种用于计算图像引导放射治疗中千伏级射线剂量的新分析方法。

A novel analytical method for computing dose from kilovoltage beams used in Image-Guided radiation therapy.

机构信息

Department of Medical Radiation Engineering, Shahid Beheshti University, Tehran, Iran.

Department of Medical Radiation Engineering, Shahid Beheshti University, Tehran, Iran.

出版信息

Phys Med. 2022 Apr;96:54-61. doi: 10.1016/j.ejmp.2022.02.020. Epub 2022 Feb 25.

Abstract

PURPOSE

A modified convolution/superposition algorithm is proposed to compute dose from the kilovoltage beams used in IGRT. The algorithm uses material-specific energy deposition kernels instead of water-energy deposition kernels.

METHODS

Monte Carlo simulation was used to model the Elekta XVI unit and determine dose deposition characteristics of its kilovoltage beams. The dosimetric results were compared with ion chamber measurements. The dose from the kilovoltage beams was then computed using convolution/superposition along with material-specific energy deposition kernels and compared with Monte Carlo and measurements. The material-specific energy deposition kernels were previously generated using Monte Carlo.

RESULTS

The obtained gamma indices (using 2%/2mm criteria for 95% of points) were lower than 1 in almost all instances which indicates good agreement between simulated and measured depth doses and profiles. The comparisons of the algorithm with measurements in a homogeneous solid water slab phantom, and that with Monte Carlo in a head and neck CT dataset produced acceptable results. The calculated point doses were within 4.2% of measurements in the homogeneous phantom. Gamma analysis of the calculated vs. Monte Carlo simulations in the head and neck phantom resulted in 94% of points passing with a 2%/2mm criteria.

CONCLUSIONS

The proposed method offers sufficient accuracy in kilovoltage beams dose calculations and has the potential to supplement the conventional megavoltage convolution/superposition algorithms for dose calculations in low energy range.

摘要

目的

提出了一种改进的卷积/叠加算法,用于计算 IGRT 中使用的千伏射线束的剂量。该算法使用材料特异性的能量沉积核,而不是水-能量沉积核。

方法

使用蒙特卡罗模拟来建模 Elekta XVI 装置,并确定其千伏射线束的剂量沉积特性。将剂量测量结果与离子室测量进行比较。然后使用卷积/叠加以及材料特异性的能量沉积核来计算千伏射线束的剂量,并与蒙特卡罗和测量结果进行比较。之前使用蒙特卡罗生成了材料特异性的能量沉积核。

结果

在几乎所有情况下,获得的伽马指数(对于 95%的点使用 2%/2mm 标准)都低于 1,这表明模拟和测量的深度剂量和分布之间有很好的一致性。该算法与水模体平板中的测量值以及与头部和颈部 CT 数据集的蒙特卡罗模拟的比较产生了可接受的结果。在均匀水模体中,计算出的点剂量与测量值相差在 4.2%以内。在头部和颈部模体中,计算出的与蒙特卡罗模拟的伽马分析结果表明,有 94%的点通过了 2%/2mm 标准。

结论

该方法在千伏射线束剂量计算中具有足够的准确性,有可能补充传统的兆伏级卷积/叠加算法,用于低能范围的剂量计算。

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