Killinger A H, Weisiger R M, Helper L C, Mansfield M E
Am J Vet Res. 1978 Jun;39(6):931-4.
The relationship between clinical infectious bovine keratoconjunctivitis (IBK) and Moraxella bovis antibodies was evaluated in a herd of calves during one summer. The detection and the distribution of antibody response in lacrimal secretions of beef calves to natural exposure of M bovis were determined by an indirect fluorescent antibody test. Three classes of immunoglobulins--secretory IgA, IgM, and IgG--were monitored in lacrimal secretions over a 5-month period when IBK was enzootic in the herd. The 3 classes of antibody to M bovis were detected in all but 2 calves at the start of the monitoring, and the highest and most persistent M bovis antibody titers were in the IgG immunoglobulin class, and less so in IgM and secretory IgA classes. The specific antibodies present in the lacrimal secretions did not prevent the development of clinical IBK in the calves.
在一个夏季，对一群犊牛临床感染性牛角膜结膜炎（IBK）与牛莫拉菌抗体之间的关系进行了评估。通过间接荧光抗体试验，测定了肉牛犊泪液分泌物中针对牛莫拉菌自然暴露的抗体反应的检测及分布情况。在该牛群中IBK呈地方流行性的5个月期间，对泪液分泌物中的三类免疫球蛋白——分泌型IgA、IgM和IgG进行了监测。在监测开始时，除2头犊牛外，所有犊牛均检测到了针对牛莫拉菌的这三类抗体，且针对牛莫拉菌的抗体效价最高且最持久的是IgG免疫球蛋白类别，IgM和分泌型IgA类别则相对较低。泪液分泌物中存在的特异性抗体并不能预防犊牛临床IBK的发生。
