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传染性牛角膜结膜炎II。自然感染或实验感染牛莫拉菌的牛泪液分泌物中的抗体。

Infectious bovine keratoconjunctivitis II. Antibodies in lacrimal secretions of cattle naturally or experimentally infected with Moraxella bovis.

作者信息

Nayar P S, Saunders J R

出版信息

Can J Comp Med. 1975 Jan;39(1):32-40.

Abstract

Preinfection, acute and convalescent phase lacrimal secretions from 20 cattle that had mild to severe keratoconjunctivitis (associated with natural or experimental Moraxella bovis infection) were tested for specific antibody to M. bovis as well as for immunoglobulins, particulary of the A class. The convalescent phase secretions from all four natural cases but from only seven of the 16 experimental cases contained increased amounts of immunoglobulins, predominantly of the A class. Only the secretions from cattle having severe keratoconjunctivitis contained precipitins specific for Moraxella bovis.Therefore, M. bovis specifically stimulates the appearance in tears of immunoglobulins that are important in the age associated, acquired resistance to reinfection with M. bovis.

摘要

对20头患有轻度至重度角结膜炎(与自然或实验性牛摩拉菌感染相关)的牛在感染前、急性期和恢复期的泪液分泌物进行检测,以检测牛摩拉菌的特异性抗体以及免疫球蛋白,尤其是A类免疫球蛋白。在所有4例自然病例的恢复期分泌物中,但在16例实验病例中只有7例的恢复期分泌物中,免疫球蛋白含量增加,主要是A类免疫球蛋白。只有患有严重角结膜炎的牛的分泌物中含有牛摩拉菌特异性沉淀素。因此,牛摩拉菌能特异性刺激泪液中免疫球蛋白的出现,这些免疫球蛋白在与年龄相关的、获得性抗牛摩拉菌再感染的抵抗力中起重要作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d25/1277411/efd8e55f462f/compmed00041-0045-a.jpg

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