Dey Indranil, Singhal Natasha, Walsh Hannah Ruth, Heaton Paul Anthony, Paul Siba Prosad
Department of Paediatrics Torbay Hospital, Torquay, UK.
Medical School, Plymouth University Peninsula Medical School, Plymouth, UK.
Sudan J Paediatr. 2021;21(2):205-208. doi: 10.24911/SJP.106-1601033976.
Fever is a natural and almost universal mammalian response to infection. There exists a fear amongst general public and healthcare providers regarding fever being harmful leading to its overzealous management with antipyretics. Although the National Institute for Health and Care Excellence (NICE) guidelines suggest the use of single antipyretic agent for management of fever, combination therapy with paracetamol, and ibuprofen is common in paediatric practice in the United Kingdom. These antipyretics at times can cause significant adverse events even when administered at regular therapeutic doses. We describe a young boy who presented with significant hypothermia (34.1°C) and was initially treated as cold sepsis. Once the boy got warmed up and as blood results became subsequently available, it became clearer that the hypothermia was secondary to therapeutic doses of antipyretics. In conclusion, we hope to improve awareness regarding this condition in clinical practice and educate health care professionals and caregivers with recommended NICE guidelines.
发热是哺乳动物对感染的一种自然且几乎普遍的反应。普通公众和医疗服务提供者都担心发热有害，从而导致对其过度使用退烧药进行处理。尽管英国国家卫生与临床优化研究所（NICE）的指南建议使用单一退烧药来治疗发热，但在英国的儿科实践中，对乙酰氨基酚和布洛芬联合治疗却很常见。这些退烧药有时即使按常规治疗剂量使用也会导致严重的不良事件。我们描述了一名体温显著过低（34.1°C）的小男孩，他最初被当作冷脓毒症进行治疗。一旦男孩体温恢复正常且后续血液检查结果出来后，就更清楚地表明体温过低是由治疗剂量的退烧药所致。总之，我们希望提高临床实践中对这种情况的认识，并根据NICE推荐的指南对医疗保健专业人员和护理人员进行教育。
