Maamri Kais, Ben Fredj Rihab, Nessib Nesrine, Trifa Amine, Hadhri Maher, Elkahla Ghassen, Ben Nsir Atef, Darmoul Mehdi
Department of Neurosurgery Fattouma Bourguiba University Hospital of Monastir Monastir Tunisia.
Clin Case Rep. 2022 Feb 16;10(2):e05472. doi: 10.1002/ccr3.5472. eCollection 2022 Feb.
Primary mucinous adenocarcinoma is an exceptionally rare neoplasm with a propensity for local recurrence and metastasis. We report the second case in the world literature of a primary mucinous adenocarcinoma of the orbit in a 66-year-old man suffering from pain, progressive protrusion of left eye, and a deep drop in vision on the left for several weeks. His first external examination revealed significant proptosis with downward displacement of the left globe with no signs of lagophthalmos. A limitation of abduction was also noted. A CT of the orbit with and without contrast showed intra- and extra-conical solid expansive process. MRI of the orbit with contrast and without contrast has shown a process of the supero-internal angle of the left orbit. The patient was operated via a combined approach, and complete enucleation was done. The final pathologic diagnosis was mucinous adenocarcinoma of the orbit. The postoperative neuroimaging showed a complete resection of the tumor. The patient is referred for adjuvant radiotherapy. A CT of the orbit was made 3 months postoperatively and did not show any local recurrence.
原发性黏液腺癌是一种极为罕见的肿瘤，易于局部复发和转移。我们报告世界文献中第二例眼眶原发性黏液腺癌病例，患者为一名66岁男性，数周来一直遭受疼痛、左眼渐进性突出及视力急剧下降的困扰。首次外部检查发现明显眼球突出，左眼眼球向下移位，无眼睑闭合不全迹象。还注意到外展受限。眼眶CT平扫及增强显示眶内和眶锥内外实性膨胀性病变。眼眶MRI平扫及增强显示左眼眶内上象限病变。患者通过联合入路进行手术，行完整眼球摘除术。最终病理诊断为眼眶黏液腺癌。术后神经影像学检查显示肿瘤完全切除。患者接受辅助放疗。术后3个月行眼眶CT检查，未显示任何局部复发迹象。
