Department of Ophthalmology, Taichung Armed Forces General Hospital, Taichung City 41168, Taiwan.
Department of Ophthalmology, Tri-Service General Hospital, National Defense Medical Center, Taipei 114, Taiwan.
Medicina (Kaunas). 2022 Feb 19;58(2):317. doi: 10.3390/medicina58020317.
Carcinosarcomas are biphasic tumors comprising carcinoma and sarcoma components that occur in many tissues but are rarely found in the orbit. A 70-year-old male presented to the ophthalmic clinic with progressive proptosis, having decreased vision in the left eye for 8 months. On examination, severe exophthalmos and lagophthalmos with limited extraocular movement were noted. Orbital computed tomography scans revealed a large, well-defined, heterogeneously enhanced mass in the left retrobulbar orbital cavity. The tumor was completely resected, and the pathological examination revealed a carcinosarcoma. The prognosis was excellent without local recurrence at 48 months postoperatively. Thus, when considering treatment for effective management of such tumors, tumor resection followed by radiotherapy or chemotherapy is highly recommended.
癌肉瘤是一种由癌和肉瘤成分组成的双相肿瘤，发生于许多组织，但在眼眶中很少见。一位 70 岁男性因进行性眼球突出就诊于眼科诊所，左眼视力下降 8 个月。检查发现严重的眼球突出和眼睑闭合不全，伴有有限的眼球运动。眼眶 CT 扫描显示左眼眶后腔有一个大的、界限清楚的、不均匀强化的肿块。肿瘤被完全切除，病理检查显示为癌肉瘤。术后 48 个月无局部复发，预后良好。因此，在考虑此类肿瘤的有效治疗方案时，强烈建议行肿瘤切除术，然后进行放疗或化疗。
