Badar Ahmed
Department of Physiology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, SAU.
Cureus. 2022 Jan 21;14(1):e21476. doi: 10.7759/cureus.21476. eCollection 2022 Jan.
Vitamin B12 is an essential vitamin. Among its many functions is its crucial role as a coenzyme in a step of normal synthesis of myelin. Likewise, it is a vital coenzyme in the synthesis of neurotransmitters. Therefore, it is no surprise that vitamin B12 deficiency is linked to a spectrum of neuropsychiatric disorders. Most physicians can quickly pick up typical pernicious anemia, but very few remember the association of vitamin B12 with neuropsychiatric disorders. In this case report, the author presents his own experience of neuropsychiatric disorder (presenting as carpal tunnel syndrome along with anxiety) related to vitamin B12 deficiency with a strong recommendation to include vitamin B12 in the initial set of laboratory investigations suggested for patients over 40 years of age presenting with neuropsychiatric disorders.
维生素B12是一种必需维生素。它有许多功能，其中作为髓鞘正常合成过程中一种辅酶发挥着关键作用。同样，它在神经递质的合成中也是一种至关重要的辅酶。因此，维生素B12缺乏与一系列神经精神障碍有关也就不足为奇了。大多数医生能够迅速识别典型的恶性贫血，但很少有人记得维生素B12与神经精神障碍之间的关联。在本病例报告中，作者介绍了自己诊治与维生素B12缺乏相关的神经精神障碍（表现为腕管综合征伴焦虑）的经历，并强烈建议在为40岁以上出现神经精神障碍的患者建议的初始实验室检查项目中纳入维生素B12检测。
