Cugini P, Letizia C, Murano G, Lucia P, Di Palma L, Scavo D
G Ital Cardiol. 1986 Feb;16(2):127-37.
The present work is devoted to investigate the meaning of disorders in renin secretion in primary and secondary hypertension and report the results of bayesan analysis applied to a group of 125 hypertensives who underwent selective renal angiography and polydistrictual renal vein samplings for the determination of plasma renin activity for diagnostic and therapeutic purposes. Data obtained from statistical analysis allow specifications on the prevalence of disorders, rates of false positives and false negatives, predictive value, diagnostic value, sensitivity and specificity. The weighted data are useful to validate the reliability of the renin renal vein measurements which are used in clinical practice for identifying the potentially surgically curable forms of arterial hypertension.
本研究致力于探讨原发性和继发性高血压中肾素分泌紊乱的意义，并报告对一组125例高血压患者进行贝叶斯分析的结果，这些患者接受了选择性肾血管造影和多区域肾静脉采样，以测定血浆肾素活性用于诊断和治疗目的。统计分析获得的数据有助于明确紊乱的患病率、假阳性和假阴性率、预测价值、诊断价值、敏感性和特异性。加权数据有助于验证肾静脉肾素测量的可靠性，该测量在临床实践中用于识别潜在可手术治愈的动脉高血压形式。
