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[单侧萎缩肾与高血压——血浆肾素测定对评估肾切除术适应证的价值]

[Unilateral atrophic kidney and hypertension--the value of plasma renin determination for assessing the indications for nephrectomy].

作者信息

Mast G J, Alloussi S, Schwaiger R, Kopper B, Ziegler M

出版信息

Z Urol Nephrol. 1985 Dec;78(12):673-80.

PMID:3913222
Abstract

In unilateral atrophic kidney and hypertension the nephrectomy is the therapy of choice. The nephrectomy is, however, indicated only then, when a causal pathogenetic connection of atrophic kidney and hypertension is proved. As criterion of the proof of such a connection according to our experiences the side-separated determination of the plasma renin activity in the venous blood of the kidneys stood the test. A renal vein renin quotient greater than 1.5, moreover, permits a rather reliable prognostic evidence concerning the behaviour of the postoperative blood pressure. In 26 out of 31 hypertensive patients with significant renal vein renin quotient who were nephrectomized for a unilateral atrophic kidney could be achieved a normalization of the blood pressure, in the other 5 patients an improvement of the blood pressure.

摘要

在单侧萎缩性肾伴高血压的情况下,肾切除术是首选的治疗方法。然而,只有在证实萎缩性肾与高血压之间存在因果发病学联系时,才进行肾切除术。根据我们的经验,作为这种联系证据的标准,对肾脏静脉血中血浆肾素活性进行侧别分离测定是经得住考验的。此外,肾静脉肾素商大于1.5,对于术后血压的变化可提供相当可靠的预后依据。在31例因单侧萎缩性肾而行肾切除术且肾静脉肾素商显著的高血压患者中,26例患者的血压恢复正常,另外5例患者的血压有所改善。

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