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慢性病患者的精神障碍共病:海洛因依赖患者与糖尿病患者的比较研究

Comorbidity of Mental Disorder in Patients with Chronic Disease: A Comparative Study of Heroin Dependence Patients and Diabetes Mellitus Patients.

作者信息

Seghatoleslam Tahereh, Ardakani Abolfazl, Habil Hussain, Rashid Rusid

机构信息

Department of Psychological Medicine, Medical Faculty, University of Malaya Centre of Addiction Sciences (UMCAS), Kuala Lumpur, Malaysia.

Department of Psychiatry, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Iran J Public Health. 2022 Jan;51(1):142-150. doi: 10.18502/ijph.v51i1.8305.

DOI:10.18502/ijph.v51i1.8305
PMID:35223635
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8837873/
Abstract

BACKGROUND

Chronic patients are at greater risk for a psychiatric problem than the normal population; yet, the increased rate of mental disorder among one chronic patient compared to another chronic patient is uncertain. We aimed to assess the rate of mental disorder among people with heroin dependence and diabetes mellitus in comparison with the healthy population.

METHODS

This cross-sectional study was carried out in Kuala Lumpur, Malaysia in 2017-2020. The study consisted of 648 participants including heroin dependence patients, diabetes mellitus patients, and healthy population. The GHQ-28 and SCL-90-R scales were used to assess mental disorder among the study populations.

RESULTS

The current study revealed the rate of mental disorder among heroin dependence patients, diabetes mellitus patients, and healthy population respectively at 52.1%, 49.5%, and 23.2% using SCL-90-R and GHQ-28. The rate of mental disorder in both heroin dependent (OR 95%= 3.59: 2.37-5.44) and diabetic groups (OR 95%=3.25: 2.14-4.92) were significantly more than the healthy population; however, the odds ratio of mental disorder was not significantly different between heroin dependent and diabetic groups. Furthermore, the results revealed an acceptable agreement between SCL-90-R and GHQ-28 to detect mental disorders (Kappa=0.60; <0.001).

CONCLUSION

People with diabetes mellitus and heroin dependence have significantly poorer mental health than healthy people in Malaysia have. Furthermore, the equivalent rate of mental disorder among such patients suggests that heroin dependence patients are not more distressed than diabetes mellitus patients are. However, further comparative studies are needed to prove these findings.

摘要

背景

慢性病患者患精神疾病的风险高于正常人群;然而,与另一位慢性病患者相比,某一慢性病患者精神障碍发病率的增加情况尚不确定。我们旨在评估海洛因依赖者和糖尿病患者中精神障碍的发病率,并与健康人群进行比较。

方法

这项横断面研究于2017 - 2020年在马来西亚吉隆坡进行。该研究包括648名参与者,其中有海洛因依赖患者、糖尿病患者和健康人群。使用一般健康问卷28项版(GHQ - 28)和症状自评量表90项修订版(SCL - 90 - R)来评估研究人群中的精神障碍。

结果

当前研究显示,使用SCL - 90 - R和GHQ - 28评估,海洛因依赖患者、糖尿病患者和健康人群中精神障碍的发病率分别为52.1%、49.5%和23.2%。海洛因依赖组(比值比95% = 3.59:2.37 - 5.44)和糖尿病组(比值比95% = 3.25:2.14 - 4.92)的精神障碍发病率均显著高于健康人群;然而,海洛因依赖组和糖尿病组之间精神障碍的比值比没有显著差异。此外,结果显示SCL - 90 - R和GHQ - 28在检测精神障碍方面具有可接受的一致性(kappa值 = 0.60;P < 0.001)。

结论

在马来西亚,糖尿病患者和海洛因依赖者的心理健康状况明显比健康人差。此外,这类患者中精神障碍发病率相当,这表明海洛因依赖患者并不比糖尿病患者更痛苦。然而,需要进一步的比较研究来证实这些发现。

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