Rutte Anne, van Splunter Maaike M I, van der Heijden Amber A W A, Welschen Laura M C, Elders Petra J M, Dekker Jacqueline M, Snoek Frank J, Enzlin Paul, Nijpels Giel
a Department of General Practice and Elderly Care Medicine, EMGO Institute for Health and Care Research VU University Medical Center , Amsterdam , The Netherlands.
J Sex Marital Ther. 2015;41(6):680-90. doi: 10.1080/0092623X.2014.966399. Epub 2014 Nov 3.
This study aimed to assess the prevalence and correlates of sexual dysfunction in a sample of Dutch men and women with type 2 diabetes. Patients with type 2 diabetes who were between the ages of 40 and 75 years from 4 Dutch diabetes centers were asked to complete self-report questionnaires covering sociodemographic characteristics, medical characteristics, clinical depression (Center for Epidemiological Studies), and sexual dysfunction (in men: International Index of Erectile Function; in women: Female Sexual Function Index). In total, 158 type 2 diabetes patients (68% men) completed the cross-sectional survey. On the basis of predefined criteria, 69% of men and 70% of women were classified with some degree of sexual dysfunction. Univariable logistic regression analyses revealed that sexual dysfunctions were associated with higher age, clinical depression (Center for Epidemiological Studies score ≥16), and one or more diabetes-related complications in both men and women. Multivariable logistic regression analyses revealed that clinical depression was most strongly associated with both male (OR = 6.87, 95% CI [1.77, 26.63]) and female (OR = 9.33, 95% CI [1.03, 84.87]) sexual dysfunction. In conclusion, sexual dysfunction is highly prevalent in men and women with type 2 diabetes and is associated with higher age, clinical depression, and diabetes-related complications. These results suggest that addressing sexual dysfunction in diabetes care is important.
本研究旨在评估荷兰2型糖尿病男性和女性样本中性功能障碍的患病率及其相关因素。来自4家荷兰糖尿病中心的年龄在40至75岁之间的2型糖尿病患者被要求完成自我报告问卷，内容涵盖社会人口学特征、医学特征、临床抑郁症（流行病学研究中心量表）和性功能障碍（男性：国际勃起功能指数；女性：女性性功能指数）。共有158名2型糖尿病患者（68%为男性）完成了横断面调查。根据预先设定的标准，69%的男性和70%的女性被归类为有某种程度的性功能障碍。单变量逻辑回归分析显示，性功能障碍在男性和女性中均与较高年龄、临床抑郁症（流行病学研究中心量表得分≥16）以及一种或多种糖尿病相关并发症有关。多变量逻辑回归分析显示，临床抑郁症与男性（比值比=6.87，95%置信区间[1.77, 26.63]）和女性（比值比=9.33，95%置信区间[1.03, 84.87]）性功能障碍的相关性最强。总之，性功能障碍在2型糖尿病男性和女性中非常普遍，并且与较高年龄、临床抑郁症和糖尿病相关并发症有关。这些结果表明，在糖尿病护理中解决性功能障碍问题很重要。
