Wibowo Johan, Heriyanto Rivaldo Steven, Wijovi Felix, Halim Devina Adella, Claudia Claudia, Marcella Elizabeth, Susanto Billy, Indrawan Michele, Heryadi Nadia Khoirunnisa, Imanuelly Michelle, Anurantha Jonathan Juniard, Hariyanto Timotius Ivan, Marcellin Chintya, Sinaga Terry Devita, Rizki Saraswati Anindita, Sieto Novia, Siregar Jeremia Immanuel, Lugito Nata Pratama Hardjo, Kurniawan Andree
Faculty of Medicine, Pelita Harapan University, Tangerang, Indonesia.
Department of Internal Medicine, Faculty of Medicine, Pelita Harapan University, Tangerang, Indonesia.
Clin Exp Vaccine Res. 2022 Jan;11(1):89-95. doi: 10.7774/cevr.2022.11.1.89. Epub 2022 Jan 31.
As coronavirus disease 2019 (COVID-19) continues to spread rapidly causing approximately 186 million confirmed cases around the world, the urgency to reach herd immunity through vaccination is increasing. However, vaccine safety is a top priority to limit the occurrence of adverse events. Henceforth, this study aims to recognize and perceive COVID-19 vaccine safety in Indonesia during the pandemic.
This is a cross-sectional study and was conducted in Indonesia during the COVID-19 pandemic using an online survey of demographic information and a qualitative questionnaire. Responses were recorded and the association between demographic characteristics from survey questions was tested using chi-square with a risk estimate and 95% confidence interval.
A total of 311 participants from 33 out of 34 provinces in Indonesia participated in this study. Recorded responses showed multiple side effects of the COVID-19 vaccine both short- and long-term experienced by the participants. Significant associations were found between demographic factors and COVID-19 vaccine side effects such as female gender with short-term puncture site (odds ratio [OR], 0.463; 95% confidence interval [CI], 0.263-0.816) and short-term other reactions (OR, 0.463; 95% CI, 0.263-0.816), domicile outside Java island with long-term puncture site (OR, 4.219; 95% CI, 1.401-12.701) and immune reactions (OR, 3.375; 95% CI, 1.356-8.398), also between married marital status and long-term vagal reaction (OR, 4.655; 95% CI, 1.321-16.409).
Gender, domicile and marital status factors were associated with COVID-19 vaccine side effects in Indonesian people.
随着2019冠状病毒病（COVID-19）继续迅速传播，在全球造成约1.86亿确诊病例，通过接种疫苗实现群体免疫的紧迫性日益增加。然而，疫苗安全是限制不良事件发生的首要任务。因此，本研究旨在认识和了解印度尼西亚在疫情期间的COVID-19疫苗安全性。
这是一项横断面研究，在印度尼西亚COVID-19疫情期间进行，采用在线调查人口统计学信息和定性问卷。记录回答情况，并使用卡方检验及风险估计和95%置信区间来检验调查问题中人口统计学特征之间的关联。
印度尼西亚34个省份中的33个省份的311名参与者参与了本研究。记录的回答显示参与者经历了COVID-19疫苗的多种短期和长期副作用。在人口统计学因素与COVID-19疫苗副作用之间发现了显著关联，如女性与短期穿刺部位副作用（优势比[OR]，0.463；95%置信区间[CI]，0.263 - 0.816）和短期其他反应（OR，0.463；95% CI，0.263 - 0.816），爪哇岛以外的居住地与长期穿刺部位副作用（OR，4.219；95% CI，1.401 - （此处原文有误，应为12.701））和免疫反应（OR，3.375；95% CI，1.356 - 8.398），以及婚姻状况与长期迷走神经反应（OR太4.655；95% CI，1.321 - 16.409）之间也存在关联。
性别、居住地和婚姻状况因素与印度尼西亚人接种COVID-19疫苗的副作用有关。 （注：原文中“also between married marital status”表述有误，应为“also between marital status” ）
